Two cases of renal
lymphoma were reported. Case 1 was a 73-year-old, and case 2 was a 59-year-old female. Their chief complaint was
flank pain. The findings obtained by CT and angiography were not compatible with
renal cancer. The tentative diagnosis of case 1 was inflammatory disease or soft tissue
tumor, and that of case 2 was renal subcapsular
tumor. Histological specimen was obtained by open biopsy from case 1, and by
nephrectomy from case 2. Immunohistochemical surface marker study revealed both
tumors were
B cell lymphoma.
Chemotherapy (
CHOP-Bleo, or PPA) in both cases and additional
radiotherapy in case 2 markedly reduced the
tumor size. Nevertheless, case 1 died 5 months later from recurrence, and case 2 died 14 months later of gastrointestinal
bleeding. At autopsy, the renal subcapsular layer was infiltrated by
lymphoma cells in both cases, and
lymphadenopathy was not observed. Reviewing 16 cases previously reported as renal
lymphoma, the capsular or subcapsular diffuse infiltration to the kidney is considered to be a characteristic feature of renal
lymphoma.