Excitatory amino acid receptors and disease.

Abstract

Recent advances in the molecular biology of excitatory amino acid receptors are reviewed. Evidence that drugs blocking the excitatory action of glutamate at the N-methyl-D-aspartate (NMDA) and non-NMDA receptors may be of clinical use in epilepsy, Parkinson's disease, cerebral ischaemia and trauma, acquired immune deficiency syndrome (AIDS) encephalopathy and neuropathic pain is summarized.

• Authors: B S Meldrum
• Journal: Current opinion in neurology and neurosurgery (Curr Opin Neurol Neurosurg) Vol. 5 Issue 4 Pg. 508-13 (Aug 1992) ISSN: 0951-7383 [Print] United States
• PMID: 1325224 (Publication Type: Journal Article, Review)

Chemical References

• Amino Acids
• Receptors, AMPA
• Receptors, Amino Acid
• Receptors, Cell Surface
• Receptors, Glutamate
• Receptors, Kainic Acid
• Receptors, N-Methyl-D-Aspartate
• Receptors, Neurotransmitter

Topics

• Amino Acids (physiology)
• Humans
• Nervous System (physiopathology)
• Nervous System Diseases (physiopathology)
• Receptors, AMPA
• Receptors, Amino Acid
• Receptors, Cell Surface (physiology)
• Receptors, Glutamate
• Receptors, Kainic Acid
• Receptors, N-Methyl-D-Aspartate (physiology)
• Receptors, Neurotransmitter (physiology)