Phase II enzyme-inducing and antioxidant activities of beetroot (Beta vulgaris L.) extracts from phenotypes of different pigmentation.

Abstract

Free-radical scavenging, reducing, and phase II enzyme-inducing activities of aqueous and 5% aqueous ethanol extracts of freeze-dried root tissue of four beet (Beta vulgaris L.) strains (red, white, orange, and high-pigment (red) phenotypes) were determined. Aqueous and ethanolic tissue extracts of the regular and high-pigment red phenotypes were most capable of inhibiting metmyoglobin/H(2)O(2)-mediated oxidation of 2-2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and 2,2'-azobis-(2-amidinopropane) dihydrochloride (AAPH)-mediated bleaching of beta-carotene. These same extracts were also most efficient at reducing ABTS radical cation and inducing quinone reductase in murine hepatoma (Hepa 1c1c7) cells in vitro.

• Authors: Mahinda Wettasinghe, Bradley Bolling, Leslie Plhak, Hang Xiao, Kirk Parkin
• Journal: Journal of agricultural and food chemistry (J Agric Food Chem) Vol. 50 Issue 23 Pg. 6704-9 (Nov 06 2002) ISSN: 0021-8561 [Print] United States
• PMID: 12405765 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Amidines
• Antioxidants
• Benzothiazoles
• Free Radicals
• Pigments, Biological
• Plant Extracts
• Sulfonic Acids
• beta Carotene
• Water
• Metmyoglobin
• 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
• Ethanol
• 2,2'-azobis(2-amidinopropane)
• Hydrogen Peroxide
• NAD(P)H Dehydrogenase (Quinone)

Topics

• Amidines (chemistry)
• Animals
• Antioxidants (analysis, pharmacology)
• Benzothiazoles
• Beta vulgaris (chemistry)
• Enzyme Induction (drug effects)
• Ethanol
• Free Radicals (chemistry)
• Hydrogen Peroxide (chemistry)
• Liver Neoplasms, Experimental
• Metmyoglobin (chemistry)
• Mice
• NAD(P)H Dehydrogenase (Quinone) (biosynthesis)
• Phenotype
• Pigments, Biological (analysis)
• Plant Extracts (chemistry, pharmacology)
• Sulfonic Acids (chemistry)
• Tumor Cells, Cultured
• Water
• beta Carotene (chemistry)