[Transcatheter arterial chemoembolization combined with external radiation for primary liver cancer].

Abstract

OBJECTIVE:

To evaluate the therapeutic efficacy of transcatheter arterial chemoembolization (TACE) combined with external radiotherapy (RT) for primary liver cancer.

METHODS:

The effectiveness of combined therapy with TACE and RT (76 cases) and TACE therapy alone (68 cases) was prospectively nonrandomly studied.

RESULTS:

In TACE + RT group, the response rate (CR + PR) was 53.9%, and the 1-, 2-, 3-year survival rate was 71.6%, 49.0%, and 44.5%, respectively. In contrast, the response rate of TACE alone was 33.8%, and the 1-, 2-, 3-year survival rate was 51.8%, 17.3%, and 17.3%, respectively. The difference between these two groups was statistically significant (P < 0.05). Factors of prognostic significance in the TACE + RT group were tumor type, tumor cell thrombi in the portal system, number of TACE treatment and the use of gelform in embolization.

CONCLUSION:

TACE + RT is more effective than TACE therapy alone. Understanding of the prognostic factors is useful for selection and management of patients.

• Authors: W Guo, M Song, E Yu
• Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] (Zhonghua Zhong Liu Za Zhi) Vol. 21 Issue 1 Pg. 25-8 (Jan 1999) ISSN: 0253-3766 [Print] China
• PMID: 11776790 (Publication Type: English Abstract, Journal Article)

Chemical References

• alpha-Fetoproteins

Topics

• Adult
• Aged
• Chemoembolization, Therapeutic
• Combined Modality Therapy
• Female
• Humans
• Liver Neoplasms (mortality, radiotherapy, therapy)
• Male
• Middle Aged
• Survival Rate
• alpha-Fetoproteins (analysis)