[Clinic intervention study on urogenital mycoplasma infection of pregnant women].

Abstract

OBJECTIVE:

To explore the hypothesis of pathogenic relationship between urogenital mycoplasma infection and adverse perinatal outcomes.

METHODS:

Four hundred and eighty-eight mycoplasma-positive pregnant women detected by culture method were randomly divided into erythromycine-intervention group and non-intervention group. Comparison was made on rate of reverse sero-conversion, of vertical transmission to mycoplasma and adverse perinatal outcomes incidence between groups.

RESULTS:

Ureaplasma urealyticum sero-conversion rate and rate of vertical-transmission in intervention group were significantly lower than in non-intervention group (P < 0.05). The incidences rates of preturm labor, post partum fever, puerperal infection and neonate pneumonia in intervention group were significantly lower than in non-intervention group (P < 0.05).

CONCLUSION:

Erythromycin is effective in control of ureaplasma urealyticum infection among pregnant women through cutting off vertical transmission passway and lowering adverse perinatal outcomes against ureaplasma urealyticum.

• Authors: Y Ye, S Tu, H Li
• Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi (Zhonghua Liu Xing Bing Xue Za Zhi) Vol. 22 Issue 4 Pg. 293-5 (Aug 2001) ISSN: 0254-6450 [Print] China
• PMID: 11718071 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Bacterial Agents
• Erythromycin

Topics

• Anti-Bacterial Agents (therapeutic use)
• Erythromycin (therapeutic use)
• Female
• Female Urogenital Diseases (drug therapy, microbiology)
• Humans
• Infectious Disease Transmission, Vertical
• Mycoplasma Infections (drug therapy, microbiology, transmission)
• Perinatal Care
• Pregnancy
• Pregnancy Complications (drug therapy)
• Treatment Outcome