Persistence of secretory antiamoebic antibodies in patients with past invasive intestinal or hepatic amoebiasis.

Abstract

In the present work, it was demonstrated that in amoebic dysentery and amoebic liver abscess patients, the secretory response is long-lasting (> 12 months); and 50% of amoebic dysentery patients developed circulating antiamoebic IgG in comparison with 100% of amoebic liver abscess individuals. A total of 83% of these individuals developed high levels of serum anti-Entamoeba histolytica IgA. However, only 10.4% of the dysentery patients showed this anti-E. histolytica antibody isotype in serum. There was no correlation between secretory and serum antiamoebic response, suggesting independent inductive and effector sites in both compartments.

• Authors: O Valenzuela, F Ramos, P Morán, E González, A Valadez, A Gómez, E I Melendro, M Ramiro, O Muñoz, C Ximénez
• Journal: Parasitology research (Parasitol Res) Vol. 87 Issue 10 Pg. 849-52 (Oct 2001) ISSN: 0932-0113 [Print] Germany
• PMID: 11688892 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Protozoan
• Immunoglobulin A
• Immunoglobulin A, Secretory
• Immunoglobulin G

Topics

• Adult
• Animals
• Antibodies, Protozoan (blood)
• Dysentery, Amebic (immunology)
• Entamoeba histolytica (immunology)
• Humans
• Immunoglobulin A (blood)
• Immunoglobulin A, Secretory (analysis)
• Immunoglobulin G (blood)
• Liver Abscess, Amebic (immunology)
• Middle Aged
• Saliva (immunology)