[Photodynamic therapy of recurrent and residual oropharyngeal and laryngeal tumors].

Abstract

Photodynamic therapy (PDT) was given to 61 patients with recurrent cancer of the tongue, oral mucosa, lower lip, oro- and nasopharynx, larynx. Photosensitizers photogem and photosens of Russian produce were employed. The radiation was given twice with the interval 24 and 48 hours, the exposure to light 3 to 30 min. The impact was external, through the instrumental canal of the fibroscope, by intracavitary and interstitial techniques. The response was assessed within 4-6 weeks after the PDT course. The effect was observed in 95.1% patients. Its duration ranged from 4 months to 5 years. Complete resorption of the tumor was achieved in 57.4%. The treatment failed in 4.9% patients.

• Authors: E F Stranadko, M I Garbuzov, V G Zenger, A N Nasedkin, N A Markichev, M V Riabov, I V Leskov
• Journal: Vestnik otorinolaringologii (Vestn Otorinolaringol) Issue 3 Pg. 36-9 ( 2001) ISSN: 0042-4668 [Print] Russia (Federation)
• Vernacular Title: Fotodinamicheskaia terapiia tetsidivnykh i "ostatochnykh" opukholeĭ orofaringolaringeal'noĭ oblasti.
• PMID: 11510044 (Publication Type: English Abstract, Journal Article)

Topics

• Aged
• Aged, 80 and over
• Carcinoma (therapy)
• Female
• Humans
• Laryngeal Neoplasms (therapy)
• Male
• Middle Aged
• Nasopharyngeal Neoplasms (therapy)
• Neoplasm, Residual
• Oropharyngeal Neoplasms (therapy)
• Phototherapy (methods)
• Treatment Outcome