Gabapentin in the treatment of hemifacial spasm.

Abstract

OBJECTIVES:

To evaluate the efficacy of gabapentin in the treatment of hemifacial spasm.

MATERIAL AND METHODS:

Twenty-three patients with hemifacial spasm not suitable for surgery or therapy with botulinum toxin were treated with gabapentin. The main efficacy parameter was the percentage of spasm reduction.

RESULTS:

A clinically significant reduction of spasms was obtained by 16 patients.

CONCLUSION:

Gabapentin was effective and safe in reducing hemifacial spasm in 16 out 23 (69.6%) patients.

• Authors: O Daniele, G Caravaglios, C Marchini, L Mucchiut, P Capus, E Natalè
• Journal: Acta neurologica Scandinavica (Acta Neurol Scand) Vol. 104 Issue 2 Pg. 110-2 (Aug 2001) ISSN: 0001-6314 [Print] Denmark
• PMID: 11493229 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Acetates
• Amines
• Anticonvulsants
• Cyclohexanecarboxylic Acids
• gamma-Aminobutyric Acid
• Gabapentin

Topics

• Acetates (therapeutic use)
• Adult
• Aged
• Amines
• Anticonvulsants (therapeutic use)
• Cyclohexanecarboxylic Acids
• Female
• Gabapentin
• Hemifacial Spasm (drug therapy)
• Humans
• Male
• Middle Aged
• Pilot Projects
• Treatment Outcome
• gamma-Aminobutyric Acid