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Delayed cutaneous hypersensitivity in patients with prostatic adenocarcinoma.

Abstract
Cell-mediated immunocompetence of patients seen for followup of adenocarcinoma of the prostate is evaluated using dinitrochlorobenzene as a contact sensitizing agent. The immune status is correlated with the presence or absence of metastatic disease. A highly significant correlation is found between the lack of immune response and the presence of metastatic carcinoma, suggesting that immunotherapy will be useful in the treatment of carcinoma of the prostate.
AuthorsJ C Huus, E D Kursh, P Poor, L Persky
JournalThe Journal of urology (J Urol) Vol. 114 Issue 1 Pg. 86-7 (Jul 1975) ISSN: 0022-5347 [Print] United States
PMID1142506 (Publication Type: Journal Article)
Chemical References
  • Dinitrochlorobenzene
Topics
  • Adenocarcinoma (immunology)
  • Aged
  • Dinitrochlorobenzene (immunology)
  • Follow-Up Studies
  • Humans
  • Hypersensitivity, Delayed
  • Immunity, Cellular
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Prostatic Neoplasms (immunology)

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