Fatal Hemoptysis during Coronary Thrombolysis.

Abstract

Cerebral hemorrhage is the most dreaded complication of coronary thrombolysis. Significant bleeding has also been described from catheter-entry sites, the retroperitoneum, and the gastrointestinal and genitourinary tracts. However, hemoptysis induced by thrombolysis has rarely been described in the literature. We present a 66-year-old male who received front-loaded tissue plasminogen activator (tPA) for acute transmural anterior wall myocardial infarction and developed massive hemoptysis from preexisting cavitary lung disease. The patient died within 5 hours. We believe this is the first case report of fatal hemoptysis induced by coronary thrombolysis. A history of cavitary lung disease may be a risk factor for life-threatening hemoptysis in patients receiving thrombolytic therapy.

• Authors: AW Basher, A Oduwole, NC Bhalodkar, B Mohideen, E Sy, A Sehonanda, Brown Jr EJ
• Journal: Journal of thrombosis and thrombolysis (J Thromb Thrombolysis) Vol. 3 Issue 1 Pg. 87-89 ( 1996) ISSN: 1573-742X [Electronic] Netherlands
• PMID: 10608042 (Publication Type: Journal Article)