[Intraoral cancer in the county of Copenhagen].

Abstract

A retrospective study of patients treated for intra-oral squamous cell carcinoma in Copenhagen county is reported. The material included 156 patients, 66 females and 90 males. Age at diagnosis varied between 35 and 95 years with a mean of 65 years. Mean age of females/males was 70/62 years. Twelve therapeutic modalities were performed; surgery, radiotherapy, chemotherapy and different combinations of these. Five year disease specific survival related to tumours' T-classification was 84% for T1, 35% for T2, 20% for T3 and 27% for T4. A statistically significant relation between the tumours' T-classification and the disease specific survival was noted (p < 0.00001). Five year disease specific survival related to N-classification was 62% for N0, 30% for N1, 25% for N2 and 0% for N3. Crude five year survival was 37% overall, 61% for patients in stage I, 32% for patients in stage II, 16% for patients in stage III and 17% for patients in stage IV. The results are similar to those achieved in other centres. Since no significant improvement has been noted in patient survival during the last five to six decades and since the therapeutic morbidity has not always been acceptable to the patients, other therapeutic principles, such as the so called minimal invasive therapy should be considered in future treatment of intra-oral cancer.

• Authors: S Charabi, B W Charabi, V H Balle, A Berthelsen, J C Thomsen
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 161 Issue 19 Pg. 2811-5 (May 10 1999) ISSN: 0041-5782 [Print] Denmark
• Vernacular Title: Intraoral cancer i Københavns Amt.
• PMID: 10412321 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Aged
• Carcinoma, Squamous Cell (mortality, therapy)
• Combined Modality Therapy
• Denmark (epidemiology)
• Female
• Humans
• Male
• Middle Aged
• Mouth Neoplasms (mortality, therapy)
• Neoplasm Recurrence, Local
• Neoplasm Staging
• Prognosis
• Retrospective Studies
• Survival Rate