Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1.
Also Known As:
DM Protein Kinase; DM-Kinase; DM1PK Protein; DMPK Protein; MDGP Protein; MDPK Protein; Myotonic Dystrophy Protein Kinase; DM Kinase; Kinase, DM Protein; Kinase, Myotonin-Protein; Myotonin Protein Kinase; Protein Kinase, DM; Protein, DM1PK; Protein, DMPK; Protein, MDGP; Protein, MDPK