Racepinephrine

A racemic mixture of d-epinephrine and l-epinephrine.

Also Known As:

Adrenaline Hydrochloride, Racemic Mixture; Adrenaline, Racemic Mixture; Epinephrine Hydrochloride, Racemic Mixture; Epinephrine, Racemic Mixture; Micronefrin; Micronephrine; Racemic Adrenaline; Racemic Epinephrine; Racepinephrine Hydrochloride; Vaponefrin; Adrenaline, Racemic; Epinephrine, Racemic; Racemic Mixture Adrenaline; Racemic Mixture Epinephrine

Networked: 130 relevant articles (17 outcomes, 20 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Korppi, Matti: 4 articles (01/2019 - 05/2006)
2.	Heikkilä, Paula: 2 articles (11/2018 - 07/2018)
3.	Mecklin, Minna: 2 articles (11/2018 - 07/2018)
4.	Carlsen, Kai-Håkon: 2 articles (03/2016 - 06/2013)
5.	Lødrup Carlsen, Karin C: 2 articles (03/2016 - 06/2013)
6.	Mowinckel, Petter: 2 articles (03/2016 - 06/2013)
7.	Arnold, Michelle: 1 article (09/2022)
8.	Micetic, Becky: 1 article (09/2022)
9.	Mody, Kartik: 1 article (09/2022)
10.	Wade, Christine: 1 article (09/2022)

Related Diseases

1.	Croup 05/01/1978 - "We conclude that nebulized racemic epinephrine is effective treatment for the acute signs of croup." 10/01/1983 - "Efficacy of racemic epinephrine in croup." 04/01/2022 - "Based on our study results, we can conclude that observing patients following treatment of croup with inhaled racemic epinephrine in the ED for less than 2 hours did not increase their risk of deterioration or need to return. " 01/01/1998 - "Recent studies have shown that discharging to home an emergency department (ED) patient with croup if the patient is clinically stable 3 to 4 hours after being treated with nebulized racemic epinephrine (NRE) is safe and cost-effective. " 11/01/1994 - "The aim of this study was to evaluate the immediate effect of inhaling racemic adrenaline to treat croup and to evaluate a scoring system. "
2.	Bronchiolitis 07/01/2000 - "Lung function (tPTEF/tE) was reduced in infants with acute bronchiolitis and improved significantly after inhaled racemic adrenaline. " 07/01/2000 - "The ratio of time to reach peak tidal expiratory flow to total expiratory time (tPTEF/tE) was significantly reduced in children with acute bronchiolitis (mean, 95% CI) (0.08, 0.05-0.10) compared to controls (0.31, 0.18-0.43), with significant improvement after inhaled racemic adrenaline 0.19 (0.13-0.25), parallel with significant clinical improvement. " 12/01/1993 - "This study demonstrates that treatment with nebulised racemic adrenaline improved oxygenation and clinical signs in hospitalised children aged less than 18 months with bronchiolitis." 11/01/2018 - "The current care guidelines for bronchiolitis had some impact on clinical practice, as the overall use of racemic adrenaline more than halved, but considerable differences remained in the four study hospitals after their publication." 06/13/2013 - "In this eight-center, randomized, double-blind trial with a 2-by-2 factorial design, we compared inhaled racemic adrenaline with inhaled saline and on-demand inhalation with fixed-schedule inhalation (up to every 2 hours) in infants (<12 months of age) with moderate-to-severe acute bronchiolitis. "
3.	Asthma (Bronchial Asthma) 10/01/2000 - "The efficacy of nebulized racemic epinephrine in children with acute asthma: a randomized, double-blind trial." 09/01/2014 - "Nonprescription racemic epinephrine for asthma." 10/01/1980 - "Inhalation of racemic epinephrine in children with asthma. " 07/01/2007 - "The following case report describes a patient in whom nebulized racemic epinephrine was used successfully to treat severe acute asthma following failure of standard first-line therapies." 05/01/2006 - "The aim of this study was to compare responses to inhaled albuterol and racemic epinephrine in infancy between children with and without asthma later in childhood. "
4.	Respiratory Sounds (Crackle) 05/05/2005 - "Racemic epinephrine resulted in significant improvement in wheezing and the total RDAI score on day 2 and over the entire stay (p < 0.05). " 11/01/1994 - "However, racemic adrenaline was significantly better than placebo in terms of improvement in total clinical score, inspiratory stridor, retractions and air entry, and should therefore be used as first-line treatment." 09/01/2016 - "Stridor was defined as mild (≤2 doses of racemic epinephrine), moderate (>2 doses of racemic epinephrine), or severe (requiring reintubation). " 10/01/1996 - "Racemic epinephrine was administered for treatment of coincident stridor. " 03/01/1995 - "Children with croup who received racemic epinephrine for the treatment of stridor at rest. "
5.	Laryngismus (Laryngospasm) 09/06/2022 - "She was admitted to the Respiratory Intensive Care Unit with acute hypoxic respiratory failure associated with stridor secondary to laryngospasm, which was unresponsive to steroids and racemic epinephrine. " 08/01/2006 - "To evaluate the efficacy of topical racemic adrenaline (RA) (Micronefrin; Bird Products, Palm Springs, CA, USA) in the control of intraoperative bleeding and the prevention of postoperative bleeding, laryngeal spasm and postoperative pain in adenoidectomy among children <6 years of age. "

Related Drugs and Biologics

1.	Racepinephrine
2.	Albuterol (Salbutamol)
3.	Epinephrine (Adrenaline)
4.	Dexamethasone (Maxidex)
5.	Oxygen (Dioxygen)
6.	Steroids
7.	dexamethasone 21-phosphate
8.	Adrenal Cortex Hormones (Corticosteroids)
9.	Bronchodilator Agents (Bronchodilators)
10.	Carbon Dioxide

Related Therapies and Procedures

1.	Intermittent Positive-Pressure Breathing
2.	Therapeutics
3.	Length of Stay
4.	Adenoidectomy
5.	Aftercare (After-Treatment)