Minichromosome Maintenance Complex Component 4

A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 7.

Also Known As:

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Chu: 1 article (04/2020)
2.	Cui, Shengyu: 1 article (04/2020)
3.	Cui, Zhiming: 1 article (04/2020)
4.	Fan, Jianbo: 1 article (04/2020)
5.	Jin, Huricha: 1 article (04/2020)
6.	Li, Weidong: 1 article (04/2020)
7.	Sun, Yuyu: 1 article (04/2020)
8.	Chen, Linxin: 1 article (06/2019)
9.	Fu, Liangmin: 1 article (06/2019)
10.	Han, Yongtao: 1 article (06/2019)

Related Diseases

1.	Pituitary Neoplasms (Pituitary Adenoma) 06/01/2019 - "A total of two key pathways, including cell cycle and DNA replication, as well as 12 key genes [DNA polymerase δ subunit 2, DNA replication licensing factor MCM4, MCM6, mitotic checkpoint serine/threonine-protein kinase BUB1, BUB1β, mitotic spindle assembly checkpoint protein MAD2A, dual specificity protein kinase TTK, M-phase inducer phosphatase 1, cell division control protein 45 homolog, cyclin-dependent kinase inhibitor 1C, pituitary tumor-transforming gene 1 protein and polo-like kinase 1] were identified. "
2.	Neoplasms (Cancer) 04/01/2020 - "It was demonstrated that C-X-C motif chemokine ligand 8, elastase, neutrophil expressed, growth factor independent 1 transcriptional repressor, Spi-1 proto-oncogene, CCAAT enhancer binding protein epsilon, GATA binding protein 1, TAL bHLH transcription factor 1, erythroid differentiation factor, minichromosome maintenance complex component 4, BTG anti-proliferation factor 2, BRCA1 DNA repair-associated, cyclin D1, chromatin assembly factor 1 subunit A, triggering receptor expressed on myeloid cells 1 and tumor protein p63 were hub genes in the top 5 IPA networks (with a score >30). "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Chromatin Assembly Factor-1
3.	Basic Helix-Loop-Helix Transcription Factors
4.	Cyclin-Dependent Kinase Inhibitor p57
5.	Intercellular Signaling Peptides and Proteins (Growth Factors)
6.	CCAAT-Enhancer-Binding Proteins
7.	cdc25 Phosphatases
8.	Cyclin D1
9.	Leukocyte Elastase (Neutrophil Elastase)
10.	Chemokines