Minichromosome Maintenance Complex Component 3

A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression.

Also Known As:

DNA Polymerase alpha Holoenzyme-associated Protein P1; DNA Replication Licensing Factor MCM3; RLF Subunit beta; DNA Polymerase alpha Holoenzyme associated Protein P1; Subunit beta, RLF; beta, RLF Subunit

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ghafouri-Fard, Soudeh: 1 article (07/2022)
2.	Hussen, Bashdar Mahmud: 1 article (07/2022)
3.	Khoshbakht, Tayyebeh: 1 article (07/2022)
4.	Samadian, Mohammad: 1 article (07/2022)
5.	Taheri, Mohammad: 1 article (07/2022)
6.	Gao, Yanjun: 1 article (12/2019)
7.	Li, Yang: 1 article (12/2019)
8.	Zhao, Hongyu: 1 article (12/2019)
9.	Chung, Leland W K: 1 article (06/2017)
10.	Duan, Peng: 1 article (06/2017)

Related Diseases

1.	Carcinogenesis 05/01/2017 - "Minichromosome maintenance complex component 3 (MCM3) was mainly implied in cell proliferation and tumorigenesis. "
2.	Hematologic Neoplasms (Hematological Malignancy) 07/05/2022 - "Minichromosome Maintenance Complex Component 3 Associated Protein Antisense 1 (MCM3AP-AS1) is an RNA gene located on 21q22.3. The sense transcript from this locus has dual roles in the pathogenesis of solid tumors and hematological malignancies. "
3.	Prostatic Neoplasms (Prostate Cancer) 06/13/2017 - "Upregulation of minichromosome maintenance complex component 3 during epithelial-to-mesenchymal transition in human prostate cancer."
4.	Neoplasms (Cancer) 07/05/2022 - "Minichromosome Maintenance Complex Component 3 Associated Protein Antisense 1 (MCM3AP-AS1) is an RNA gene located on 21q22.3. The sense transcript from this locus has dual roles in the pathogenesis of solid tumors and hematological malignancies. "
5.	Liver Neoplasms (Liver Cancer) 12/13/2019 - "The role of long non-coding RNA (lncRNA) Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) Antisense RNA 1 (MCM3AP-AS1) has been analyzed in liver cancer. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Long Noncoding RNA
3.	Antisense RNA (Anti-Sense RNA)
4.	RNA (Ribonucleic Acid)