Heavy Ion Radiotherapy

The use of a heavy ion particle beam for radiotherapy, such as the HEAVY IONS of CARBON.

Also Known As:

Carbon Ion Radiation Therapy; Carbon Ion Radiotherapy; Carbon Ion Therapy; Heavy Ion Radiation Therapy; Heavy Ion Therapy; Carbon Ion Therapies; Heavy Ion Radiotherapies; Heavy Ion Therapies; Radiotherapies, Heavy Ion; Radiotherapy, Carbon Ion; Radiotherapy, Heavy Ion; Therapies, Carbon Ion; Therapies, Heavy Ion; Therapy, Carbon Ion; Therapy, Heavy Ion

Networked: 876 relevant articles (115 outcomes, 212 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Radiotherapy: 166557
  - Heavy Ion Radiotherapy: 876
    - Proton Therapy: 2981

Experts

1.	Kamada, Tadashi: 161 articles (07/2022 - 11/2002)
2.	Ohno, Tatsuya: 137 articles (08/2022 - 12/2004)
3.	Tsuji, Hiroshi: 124 articles (10/2022 - 11/2002)
4.	Tsujii, Hirohiko: 106 articles (03/2020 - 02/2002)
5.	Nakano, Takashi: 103 articles (01/2022 - 06/2006)
6.	Debus, Jürgen: 63 articles (01/2022 - 05/2002)
7.	Yamada, Shigeru: 57 articles (10/2022 - 11/2002)
8.	Koto, Masashi: 41 articles (10/2022 - 02/2002)
9.	Shiba, Shintaro: 39 articles (08/2022 - 05/2015)
10.	Saitoh, Jun-Ichi: 39 articles (03/2022 - 01/2015)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2021 - "Highly conformal scanned Carbon Ion Radiotherapy (CIRT) might permit dose escalation and improved local control in advanced stage thoracic tumors, but is challenged by target motion. " 01/01/2022 - "The patient achieved complete tumor disappearance within 1 year after carbon ion radiotherapy and remained disease-free thereafter. " 10/18/2016 - "Carbon ion radiotherapy has been shown to be effective against radiotherapy-resistant tumors owing to its excellent dose concentration and high biological effect. " 03/01/2019 - "In our experience, carbon ion radiotherapy is an effective and safe option, especially in cases of tumor at high risk for local relapse, in patients with multiple local recurrences, and in patients who refuse destructive surgery." 08/01/2012 - "Through clinical experiences of carbon ion radiotherapy at the National Institute of Radiological Sciences and Gesellschaft für Schwerionenforschung, a significant reduction in the overall treatment time with acceptable toxicities has been obtained in almost all types of tumors. "
2.	Chordoma 05/01/2016 - "Carbon ion radiation therapy was safe and effective for unresectable chordoma and provided good local control and survival while preserving ambulation." 11/01/2014 - "Carbon ion therapy appears to be a safe and effective treatment for patients with skull base chordoma, resulting in high LC and OS rates." 12/01/2009 - "A carbon ion radiotherapy is an effective treatment for chordomas of the skull base with minimal side effects. " 01/01/2020 - "• Proton and carbon ion therapy are effective and safe in skull base chordoma.• Prognostic factors are GTV, organs at risk compression, and dose coverage.• Dual particle therapy and customized strategy was adopted." 05/01/2019 - "However, carbon ion radiotherapy (CIRT) has recently emerged as a promising treatment for unresectable sacral chordoma. "
3.	Sarcoma (Soft Tissue Sarcoma) 04/01/2018 - "Although this case had a poorer outcome compared with cases of the more-common sarcoma types, our experience suggested that carbon-ion radiotherapy is potentially beneficial in unresectable undifferentiated sarcomas cases of sphenoid sinus." 11/15/2002 - "Carbon ion radiotherapy seems to be a safe and effective modality in the management of bone and soft tissue sarcomas not eligible for surgical resection, providing good local control and offering a survival advantage without unacceptable morbidity." 10/25/2022 - "The data indicated that carbon ion radiotherapy was safe and effective for bone sarcomas, showing promising results for local control, overall survival, and lower acute and late toxicity. " 04/01/2010 - "To evaluate the usefulness of the dose-volume histogram (DVH) and dose-surface histogram (DSH) as clinically relevant and available parameters that helped to identify bone and soft tissue sarcoma patients at risk of developing late skin reactions, including ulceration, when treated with carbon ion radiotherapy. " 02/01/2017 - "The efficacy of carbon ion radiotherapy (CIRT) for bone and soft tissue sarcoma has been reported recently. "
4.	Rectal Neoplasms (Rectal Cancer) 08/01/2009 - "Carbon ion radiotherapy seems to be a safe and effective modality in the management of locally recurrent rectal cancer, providing good local control and offering a survival advantage without unacceptable morbidity." 07/01/2022 - "Conclusion: DW-MRI showed promising results in predicting carbon ion radiotherapy outcome in local recurrence of rectal cancer, particularly with regard to b1000 h-median, b1000 h-interquartile range and ADC h-kurtosis. " 01/01/2016 - "Carbon-ion radiation therapy may be a safe and effective treatment option for locally recurrent rectal cancer and may serve as an alternative to surgery." 01/01/2022 - "This study aimed to assess the safety and efficacy of carbon-ion radiotherapy (CIRT) for salvage of previously X-ray-irradiated (XRT) locally recurrent rectal cancer (LRRC). " 05/01/2020 - "This study aimed at evaluating the safety and efficacy of re-irradiation with Carbon Ion Radiotherapy (CIRT) in rectal cancer patients with local recurrence. "
5.	Melanoma (Melanoma, Malignant) 05/01/2009 - "Carbon ion radiotherapy is a safe and effective treatment for mucosal malignant melanoma of the head and neck in terms of high local control and acceptable toxicities. " 01/01/2023 - "Carbon-ion radiotherapy (C-ion RT) is effective for head and neck mucosal melanoma (HN-MM), including radioresistant mucosal melanoma. " 02/03/2020 - "Safety and Efficacy of Salvage Neck Dissection Following Carbon-ion Radiotherapy with Chemotherapy for a Patient with Mucosal Malignant Melanoma of Head and Neck." 10/01/2017 - "Usefulness of 11C-methionine-PET for predicting the efficacy of carbon ion radiation therapy for head and neck mucosal malignant melanoma." 05/01/2009 - "To evaluate the efficacy of carbon ion radiotherapy for mucosal malignant melanoma of the head and neck. "

Related Drugs and Biologics

1.	Protons (Proton)
2.	Metals
3.	Dacarbazine (DIC)
4.	Nimustine
5.	Vincristine (Oncovin)
6.	Immune Checkpoint Inhibitors
7.	Bevacizumab (Avastin)
8.	Amino Acid Transport System A
9.	Radioisotopes (Radionuclides)
10.	Antineoplastic Agents (Antineoplastics)

Related Therapies and Procedures

1.	Radiotherapy
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)
4.	Re-Irradiation
5.	Proton Therapy