Alternariosis

Opportunistic fungal infection by a member of ALTERNARIA genus.

Also Known As:

Dermal Alternariosis; Subcutaneous Alternariosis; Alternarioses; Alternarioses, Cutaneous; Alternarioses, Dermal; Alternarioses, Subcutaneous; Alternariosis, Cutaneous; Alternariosis, Dermal; Alternariosis, Subcutaneous; Cutaneous Alternarioses; Dermal Alternarioses; Subcutaneous Alternarioses; Cutaneous Alternariosis

Networked: 50 relevant articles (3 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Diabetes Mellitus
2.	Histoplasmosis
3.	Coccidioidomycosis
4.	Corneal Perforation
5.	Invasive Pulmonary Aspergillosis

Experts

1.	Santiago, Felicidade: 2 articles (11/2021 - 11/2010)
2.	Gomes, Tiago: 1 article (11/2021)
3.	Kieselová, Katarína: 1 article (11/2021)
4.	Martinha, Henrique: 1 article (11/2021)
5.	Fukumoto, Takeshi: 1 article (05/2021)
6.	Harada, Tomoka: 1 article (05/2021)
7.	Nakamura, Korefumi: 1 article (05/2021)
8.	Nishigori, Chikako: 1 article (05/2021)
9.	Ohnuma, Kenichiro: 1 article (05/2021)
10.	Alastruey-Izquierdo, Ana: 1 article (02/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Alternariosis:

1.	Itraconazole (Sporanox)FDA LinkGeneric 12/01/2020 - "The patient was treated for cutaneous alternariosis with itraconazole for 12 weeks and demonstrated significant improvement of the lesions. " 08/11/2023 - "This paper presents the first case report from Romania of an itraconazole nonresponsive cutaneous alternariosis in a patient without any type of immunosuppression. " 04/15/2001 - "We review the literature regarding the role of diabetes mellitus in cutaneous alternariosis and regarding the efficacy of treatment with itraconazole, which has been used very successfully. " 04/15/2001 - "A case of cutaneous ulcerative alternariosis: rare association with diabetes mellitus and unusual failure of itraconazole treatment." 01/01/2001 - "Alternariosis refractory to itraconazole in a patient suffering from bullous pemphigoid."
2.	liposomal amphotericin B FDA Link 01/01/2003 - "Relapsing cutaneous alternariosis in a kidney transplant recipient cured with liposomal amphotericin B."
3.	enilconazole (imazalil)IBA 03/01/1986 - "Studies with a plant fungicide, imazalil, with vapor-phase activity, in the therapy of human alternariosis." 03/01/1986 - "The use of a plant fungicide, the imidazole imazalil, in the therapy of human alternariosis is described. "
4.	SteroidsIBA 01/01/2007 - "Besides the patient's own disease, the use of systemic steroid use might be a possible predisposing factor for the development of cutaneous alternariosis." 09/01/1995 - "The protracted course of our patient's condition and a review of the literature suggest the tapering or stopping of steroids as the first step in the successful and permanent treatment of cutaneous alternariosis." 01/01/1990 - "We have presented a case of invasive cutaneous alternariosis in a patient receiving chronic oral steroid therapy. " 01/01/2005 - "We describe a case of dermal cutaneous alternariosis in a 70-year-old patient, who was on systemic steroid administration for autoimmune hemolytic anemia. " 01/01/2007 - "We report here the first case of cutaneous alternariosis in a 30-year-old woman who was on systemic steroid therapy for active systemic lupus erythematosus. "
5.	Adrenal Cortex Hormones (Corticosteroids)IBA 11/02/2021 - "The authors describe two clinically distinct cases of cutaneous alternariosis caused by Alternaria infectoria in patients under prolonged corticosteroid treatment. " 01/01/1996 - "Cutaneous alternariosis: role of corticosteroid-induced cutaneous fragility." 07/01/1995 - "Cutaneous alternariosis occurring in a patient treated with local intrarectal corticosteroids." 08/01/1993 - "Subcutaneous alternariosis of the foot in a patient on corticosteroids." 01/01/2011 - "Cutaneous alternariosis is an opportunistic infection that has been described mainly in patients treated with corticosteroids. "
6.	Fluconazole (Zonal)FDA LinkGeneric 07/01/2013 - "Cutaneous alternariosis in an immunocompetent patient successfully treated with oral fluconazole." 09/01/2005 - "To our knowledge, this is the first case of cutaneous alternariosis in CGD and the response to fluconazole, a drug not usually used for this mycosis." 06/01/1993 - "We report a case of cutaneous alternariosis that occurred during neutropenia in an allogeneic BMT patient receiving antifungal prophylaxis with fluconazole. "
7.	Terbinafine (Lamisil)FDA LinkGeneric 11/01/2000 - "Effectiveness of terbinafine in cutaneous alternariosis." 04/01/2000 - "Effectiveness of terbinafine in cutaneous alternariosis." 05/01/2021 - "Successful thermotherapy combined with terbinafine hydrochloride 1% cream for cutaneous alternariosis in a post-transplantation patient."
8.	posaconazole FDA Link 03/01/2017 - "Here we report on a case of cutaneous alternariosis in a renal transplant recipient treated with a newer antifungal, posaconazole. " 03/01/2017 - "Cutaneous alternariosis in a renal transplant patient successfully treated with posaconazole: Case report and literature review." 04/01/2017 - "Successful Posaconazole Therapy of Disseminated Alternariosis due to Alternaria infectoria in a Heart Transplant Recipient."
9.	Plasma GasesIBA 10/17/2017 - "Cutaneous alternariosis in an immunocompromised dog successfully treated with cold plasma and cessation of immunosuppressive medication."
10.	Therapeutic UsesIBA 11/15/1972 - "Therapeutic effect of kinetin on tobacco alternariosis."

Therapies and Procedures

1.	Therapeutics 01/01/2008 - "The main interest in this case is the rareness of the cutaneous alternariosis and of its clinical aspects and the good response to therapy. " 03/01/1992 - "Twenty-seven of 28 evaluable patients with paracoccidioidomycosis, 13 of 19 with sporotrichosis, 14 of 16 with coccidioidomycosis, and eight of eight with histoplasmosis demonstrated objective responses to therapy, as did one patient each with zygomycosis and alternariosis. " 03/01/1986 - "Studies with a plant fungicide, imazalil, with vapor-phase activity, in the therapy of human alternariosis." 04/01/2017 - "Successful Posaconazole Therapy of Disseminated Alternariosis due to Alternaria infectoria in a Heart Transplant Recipient." 01/01/1990 - "We have presented a case of invasive cutaneous alternariosis in a patient receiving chronic oral steroid therapy. "
2.	Liver Transplantation 06/01/2006 - "We describe the case of a liver transplant patient with a cutaneous alternariosis due to Alternaria infectoria. " 06/01/2006 - "Cutaneous alternariosis in a liver transplant recipient." 12/15/2001 - "Only four cases of alternariosis after orthotopic liver transplantation have been reported. " 12/15/2001 - "Alternariosis after liver transplantation." 07/01/1998 - "We report a case of cutaneous alternariosis after liver transplantation. "
3.	Kidney Transplantation 01/01/2008 - "Cutaneous alternariosis in a kidney transplantation recipient: report of a case." 11/01/2005 - "A case of subcutaneous alternariosis caused by Alternaria alternata is reported in a 52-year-old male who underwent kidney transplantation 1 year earlier. " 01/01/1995 - "Cutaneous alternariosis after renal transplantation."
4.	Mohs Surgery (Mohs' Micrographic Surgery) 02/01/2013 - "Mohs micrographic surgery for the treatment of localized cutaneous alternariosis." 03/01/2016 - "Refractory Cutaneous Alternariosis Successfully Treated With Mohs Surgery and Full-Thickness Skin Grafting."
5.	Induced Hyperthermia (Thermotherapy) 09/01/2011 - "A case of alternariosis successfully treated with local hyperthermia." 05/01/2021 - "Successful thermotherapy combined with terbinafine hydrochloride 1% cream for cutaneous alternariosis in a post-transplantation patient."