A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
Also Known As:
Proteinase 3; Azurophil Granule Protein 7; C-ANCA Antigen; Leukocyte Proteinase 3; Myeloblastin, Human; N-Proteinase 4; Neutrophil Proteinase 3, Human; Neutrophil Proteinase 4; PRTN3 Gene Protein; Antigen, C-ANCA; Autoantigen, Wegener; C ANCA Antigen; Human Myeloblastin; N Proteinase 4; Protein, PRTN3 Gene; Proteinase 3, Leukocyte; Proteinase 3, Neutrophil; Proteinase 4, Neutrophil; Neutrophil Proteinase 3; Wegener Autoantigen