Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
Also Known As:
Mannose-Binding Protein-Associated Serine Protease; MASP Proteases; MASP-Related Protein; MASPs; MBL-Associated Serine Proteases; MBP-Associated Serine Protease; MBP-Associated Serine Protease-Related Protein; Mannan-Binding Lectin Serine Proteases; MASP Related Protein; MBL Associated Serine Proteases; MBP Associated Serine Protease; MBP Associated Serine Protease Related Protein; Mannan Binding Lectin Serine Proteases; Mannose Binding Protein Associated Serine Protease; Proteases, MASP; Protein, MASP-Related; Serine Protease, MBP-Associated; Serine Proteases, MBL-Associated; MASP