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Distamycins

Oligopeptide antibiotics from Streptomyces distallicus. Their binding to DNA inhibits synthesis of nucleic acids.

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Distamycins: 2

Experts

1.	Ali, Asfa: 1 article (05/2016)
2.	Bhan, Arunoday: 1 article (05/2016)
3.	Bhattacharya, Santanu: 1 article (05/2016)
4.	Kamra, Mohini: 1 article (05/2016)
5.	Mandal, Subhrangsu S: 1 article (05/2016)

Related Diseases

1.	Neoplasms (Cancer) 05/31/2016 - "New Fe(iii) and Co(ii) salen complexes with pendant distamycins: selective targeting of cancer cells by DNA damage and mitochondrial pathways."
2.	Breast Neoplasms (Breast Cancer) 05/01/1975 - "Rifamycins and distamycins were assayed in vitro for their effects on the activity of a reverse transcriptase derived from the plasma of a patient with breast cancer. "

Related Drugs and Biologics

1.	Rifamycins
2.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
3.	disalicylaldehyde ethylenediamine (salen)