Central Nervous System Agents
A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)
Also Known As:
Central Nervous System Drugs
Networked: 51
relevant articles (3 outcomes,
9 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Preskorn, Sheldon H:
2 articles
(01/2022 - 01/2017)
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2. | Chien, Edward K:
1 article
(12/2022)
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3. | Gerlanc, Nicole:
1 article
(12/2022)
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4. | Grantz, Katherine L:
1 article
(12/2022)
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5. | Grewal, Jagteshwar:
1 article
(12/2022)
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6. | Grobman, William A:
1 article
(12/2022)
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7. | Hinkle, Stefanie N:
1 article
(12/2022)
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8. | Newman, Roger B:
1 article
(12/2022)
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9. | Ranzini, Angela C:
1 article
(12/2022)
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10. | Sciscione, Anthony:
1 article
(12/2022)
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Related Diseases
1. | Mental Disorders (Mental Disorder)
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2. | Neurodegenerative Diseases (Neurodegenerative Disease)
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3. | Communicable Diseases (Infectious Diseases)
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4. | Neoplasms (Cancer)
01/14/2019
- " We concluded that Some Central Nervous system drugs show a great potential as anti-cancer in vitro, in vivo and clinical trials through different mechanisms and pathways in different types of cancer that reveal a promising evidence for the repurposing of CNS drugs for new indications." 01/14/2019
- " In our review, we will review the anti-cancer effect of some CNS drugs, including both therapeutic and preventive, by searching the literature for preclinical or clinical evidence for anticancer potential of central nervous system drugs over the last 8 years period (2010-2018) and including only evidence from Q1 journals as indicated by Scimago website (www.scimagojr.com). " 04/01/2014
- " Furthermore, while anti-cancer drugs altered [methyl-(3)H]choline uptake, central nervous system drugs did not affect [methyl-(3)H]choline uptake." 04/01/2014
- " In addition, we examined the influence of anti-cancer drugs and central nervous system drugs on the transport of [methyl-(3)H]choline. " 01/01/2022
- " In these articles, we have shown that case reports often involved long-term or semi-long-term treatments such as cancer or human immunodeficiency virus therapies, antiepileptic drugs, or central nervous system drugs. "
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5. | Dementia (Dementias)
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Related Drugs and Biologics
Related Therapies and Procedures