Percutaneous Collagen Induction

04/03/2016 - " our outcome 'Participant-reported scar improvement' in one study fractional laser was more effective in producing scar improvement than non-fractional non-ablative laser at week 24 (risk ratio (RR) 4.00, 95% confidence interval (CI) 1.25 to 12.84; n = 64; very low-quality evidence); fractional laser showed comparable scar improvement to fractional radiofrequency in one study at week eight (RR 0.78, 95% CI 0.36 to 1.68; n = 40; very low-quality evidence) and was comparable to combined chemical peeling with skin needling in a different study at week 48 (RR 1.00, 95% CI 0.60 to 1.67; n = 26; very low-quality evidence). "
12/01/2020 - "Further high-quality studies should be conducted to verify/quantify the efficacy of this method, to better understand the underlying mechanisms of action underlying the effects of scar needling and to establish an effective intervention protocol."
04/01/2020 - "Quantitative analysis of 241 participants across six included studies showed a statistically significant reduction in scar severity scores in favor of microneedling or subcision with PRP (P < .001). "
09/01/2017 - "There was a statistically significant improvement in the appearance of atrophic scars, with reduction in the scores associated with the clinical evaluation scale for atrophic scarring in all groups, but the improvement was more obvious in group III. Although a single treatment may give good results, combination between skin needling and platelet-rich plasma is more effective, safe with less number of sessions in all types of atrophic scars."
01/01/2021 - "The current comprehensive literature review is intended to analyze the scientific basis supporting this therapeutic modality and to evaluate the efficacy of PCI microneedling therapy versus no treatment of patients with photoaged skin and scars of various etiologies on aesthetic skin rejuvenation, skin tightening and scar quality in prospective, retrospective and experimental studies. "

05/12/2017 - "Fire acupuncture with centro-square needles has relatively high cured and remarkable effective rate for KOA, with rapid onset; as for pain relief, the efficacy is superior to filiform needling."
10/01/2000 - "The efficacy of ESWT and needling has still to be proven.||| Patients with persisting pain after steps 1 and 2 are candidates for surgical||| removal of the deposit. "
12/31/2022 - "Only the pain scores in the fire needling, bloodletting, and herbal medicine combination groups demonstrated significant improvement. "
01/01/2022 - "The application of a needling intervention eliciting LTRs was associated with a significant reduction in pain intensity immediately after treatment (mean difference (MD): -2.03 points, 95% confidence interval (CI): -3.77 to -0.29; standardized MD (SMD): -1.35, 95% CI: -2.32 to -0.38, p = 0.02) when compared to the same needling intervention without elicitation of LTRs. "
01/01/2020 - "Foot Pain domain improved at all time points for DN group (p<0.001; 29.7 (17.8 to 41.5)) and percutaneous needling electrolysis group (p<0.001; 32.7 (18.3 to 47.0)), without significant differences between groups. "

12/01/2019 - "At 24 weeks, the treatment group achieved a statistically significant improvement in acne scores over microneedling alone. "
10/01/2023 - "The perception that microneedling will exacerbate the disease state and trigger more acneic lesions via the spread of acne-associated microbes has hindered research investigating whether microneedling is a safe and effective treatment. "
10/01/2023 - "Study to determine the safety and efficacy of microneedling as an effective treatment for acne vulgaris."
10/01/2023 - "Test the safety and efficacy of microneedling as an effective treatment modality for acne vulgaris. "
07/01/2014 - "Fractional radiofrequency microneedling is a safe and effective treatment for acne vulgaris. "

11/01/2017 - "Amnion enhanced the efficacy of MMC-modulated trabeculectomy in terms of eyes with complete success and lesser interventions such as bleb needling. "
12/01/2018 - "Bleb needling augmented with MMC can achieve a significant reduction in IOP in eyes with late trabeculectomy failure. "
03/01/1999 - "In both cases, intraocular pressure was successfully lowered for 6 months until the occurrence of bleb encapsulation, which was relieved by transconjunctival needling. "
07/01/1985 - "Nine of 13 eyes were treated successfully with primary needling of the bleb. "
08/15/2012 - "It has been suggested that needling of an encapsulated bleb may be effective in re-establishing drainage and lowering intraocular pressure. "

06/01/2020 - "Microneedling is a valuable tool that can be used in transdermal drug delivery in vitiligo patients to improve drug permeability and efficacy with minor side effects. "
11/01/2020 - "Vitiligo effectively treated with electrocautery needling technique."
08/01/2020 - "Electrocautery needling monotherapy was effective in treating vitiligo, and its efficacy was enhanced when combined with the 308-nm excimer lamp. "
01/01/2023 - "Surrounding needling in combination with NBUVB phototherapy may be a promising treatment for chronic stable nonsegmental vitiligo. "
04/01/2017 - "Improvement in moderate to severe vitiligo using a novel combination of 308 nm excimer laser and a surgical needling technique."