Bulk Drugs

Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging of a drug, becomes an active ingredient or a finished dosage form of the drug. Does not include intermediates used in the synthesis of such substances.

Also Known As:

Networked: 98 relevant articles (9 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cardoso, Catarina: 3 articles (04/2022 - 10/2021)
2.	Veloso, Cláudia: 3 articles (04/2022 - 10/2021)
3.	Vitorino, Carla: 3 articles (04/2022 - 10/2021)
4.	Andrade, Paula B: 2 articles (04/2022 - 03/2022)
5.	Videira, Romeu A: 2 articles (04/2022 - 03/2022)
6.	Zur, Eyal: 2 articles (03/2019 - 01/2019)
7.	Plata-Salamán, Carlos: 2 articles (09/2018 - 06/2018)
8.	Videla, Sebastián: 2 articles (09/2018 - 06/2018)
9.	Gao, Xiumei: 1 article (07/2022)
10.	Han, Lifeng: 1 article (07/2022)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2023 - "Nanomedicines have been further developed for more precise regulation of tumor vasculature with the capacity of co-delivering multiple active pharmaceutical ingredients, which overall reduces the systemic toxicity and boosts the therapeutic efficacy of free drugs. " 01/01/2022 - "There are many advantages to using active pharmaceutical ingredients (APIs) in the production of ILs for drug delivery, including the ability to tailor solubility, improve thermal stability, increase dissolution, regulate drug release, improve API permeability, and modulate cytotoxicity on tumor cells. " 10/09/2018 - "Nanomedicine enables site-specific delivery of active pharmaceutical ingredients and facilitates entrapment inside the tumor. " 06/08/2021 - "Multiple studies have demonstrated that thiomer-rich nanoformulations can overcome major drawbacks found when administering diverse active pharmaceutical ingredients (APIs), especially in cancer therapy. " 10/15/2020 - "We report studies on the effect of small-molecule active pharmaceutical ingredients (APIs) of human cancer therapeutics on the catalytic activity of AspH using a high-throughput mass spectrometry (MS)-based inhibition assay. "
2.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/01/2017 - "This study evaluated the efficacy of a repeated oral treatment with two active pharmaceutical ingredients (Lcr Lenio® and Lcr Restituo® ) derivated from the probiotic bacterial strain Lactobacillus rhamnosus Lcr35® in two animal models mimicking different features of irritable bowel syndrome (IBS). "
3.	Wounds and Injuries (Trauma) 12/19/2021 - "Active pharmaceutical ingredients (API) in the form of progenitor cell derivatives such as lysates and lyophilizates were shown to retain function in controlled cellular models of wound repair. " 10/01/2021 - "The incorporation of active pharmaceutical ingredients (APIs) with polymeric composition of suture materials is an efficient way to reduce inflammatory reaction in the wound site as well as to control bacterial growth, while allowing wound healing. " 12/01/2019 - "STATEMENT OF SIGNIFICANCE: This work shows the preparation and characterization of bilayer wound dressings comprising dual-biological function active pharmaceutical ingredients based on ionic liquids with improved and controlled drug release and dual therapeutic efficiency. " 08/07/2020 - "The investigation of fibers based on pure hyaluronic acid without additional polymers and with active pharmaceutical ingredients will lay the groundwork for the development of highly effective wound dressings and new drug delivery scaffolds."
4.	Virus Diseases (Viral Diseases) 01/01/2022 - "In recent years, many medicinal plants and their active pharmaceutical ingredients have been found to be effective in the treatment and prevention of viral diseases in aquatic animals. " 01/01/2022 - "Peptides and peptide-based materials have an increasing role in the treatment of viral infections through their use as active pharmaceutical ingredients, targeting moieties, excipients, carriers, or structural components in drug delivery systems. " 09/26/2023 - "Many purine derivatives are active pharmaceutical ingredients of significant importance in the therapy of autoimmune diseases, cancers, and viral infections. "
5.	COVID-19 12/01/2022 - "The coronavirus pandemic prompted scientists to look for active pharmaceutical ingredients that could be effective in treating COVID-19. " 05/18/2023 - "The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. " 11/01/2021 - "Health supply chains, the import of active pharmaceutical ingredients, transportation, procurement, finished products have been disrupted by COVID-19. "

Related Drugs and Biologics

1.	Ionic Liquids
2.	Cytotoxins (Cytolysins)
3.	Valsartan (Vals)
4.	sacubitril and valsartan sodium hydrate drug combination
5.	posaconazole
6.	benzonidazole (benznidazole)
7.	sacubitril
8.	Niacinamide (Nicotinamide)
9.	Metronidazole (Metric)
10.	Liposomes (Liposome)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Pain Management
4.	Transdermal Patch
5.	Sutures (Suture)