Fibula Fractures

Fractures of the FIBULA.

Also Known As:

Dislocation, Maisonneuve Fracture; Fibula Fracture; Fibula Shaft Fracture; Fracture Dislocation, Maisonneuve; Fracture, Fibula; Fracture, Fibula Shaft; Fracture, Maisonneuve; Shaft Fracture, Fibula; Fibula Shaft Fractures; Maisonneuve Fracture; Maisonneuve Fracture Dislocation

Networked: 99 relevant articles (8 outcomes, 8 trials/studies)

Relationship Network

Disease Context: Research Results

Wounds and Injuries: 176426
- Bone Fractures: 3857
  - Fibula Fractures: 99

Related Diseases

1.	Open Fractures (Compound Fracture)
2.	Infections
3.	Rupture
4.	Wounds and Injuries (Trauma)
5.	Ankle Fractures

Experts

1.	Liu, Yanshi: 2 articles (01/2021 - 09/2016)
2.	Hester, Robert L: 2 articles (11/2020 - 03/2014)
3.	Parekh, Selene G: 2 articles (08/2019 - 11/2013)
4.	Xiang, Lusha: 2 articles (01/2018 - 03/2014)
5.	Attia, Ahmed Khalil: 1 article (10/2022)
6.	Aydogan, Umur: 1 article (10/2022)
7.	Fayed, Aly: 1 article (10/2022)
8.	Juliano, Paul: 1 article (10/2022)
9.	Labib, Sameh A: 1 article (10/2022)
10.	Mahmoud, Karim: 1 article (10/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Fibula Fractures:

1.	Oxygen (Dioxygen)IBA 01/01/2011 - "Thus, the results of this study demonstrated that the infusion of allogeneic BMSC, expanded in vitro at different oxygen concentrations, into the site of fracture improved osteocartilaginous fragment and BC formation and bone size restoration in rats with fibula fracture." 03/01/2012 - "A 22-year-old man on postoperative day 1 after open reduction with internal fixation of a distal fibula fracture presented with hemoptysis and increased oxygen demand. "
2.	salicylhydroxamic acid (SHAM)IBA 09/01/2014 - "Radiographic evidence showed an improved hard callus bridging across fibula fractures in OVX rats treated with PEMF as compared to sham treatments. "
3.	Activins (Activin)IBA 08/01/1999 - "The present study investigates the effects of topical application of activin on fracture healing using rat fibula fracture models. " 06/30/2001 - "Local injection of activin promoted fracture healing in rat fibula fracture models. " 08/01/1999 - "Local administration of activin promotes fracture healing in the rat fibula fracture model."
4.	Stainless Steel (Steel, Stainless)IBA 05/01/2016 - "Torsional Failure of Carbon Fiber Composite Plates Versus Stainless Steel Plates for Comminuted Distal Fibula Fractures." 05/01/2016 - "The objective of this cadaveric study was to compare torsional failure properties of bridge plating a comminuted distal fibula fracture with carbon fiber polyetheretherketone (PEEK) composite and stainless steel one-third tubular plates. " 06/01/2018 - "When fibula fractures require operative fixation, implants are typically made from stainless steel or titanium alloys. " 05/01/2016 - "In a comminuted human fibula fracture fixation model, carbon fiber implants exhibited multiple pre-peak failures at significantly lower angles than the first failure for the stainless steel implants, with some delamination of composite layers and brittle catastrophic failure rather than plastic deformation. "
5.	ElementsIBA 08/01/2023 - "Biomechanical analysis of different internal fixation methods for special Maisonneuve fracture of the ankle joint based on finite element analysis." 08/18/2023 - "This study aims to evaluate the effects of ankle ligament ruptures on ankle joints, fracture instability, and plate stress after distal fibula fracture fixed with plate created by finite element analysis (FEA) modeling and loading applied to ligament rupture models that may accompany this fracture. "
6.	polyetheretherketoneIBA 05/01/2020 - "In the literature, there are abundant data about CFR/PEEK plates in the treatment of proximal humerus, distal radius and distal fibula fractures. " 05/01/2016 - "The objective of this cadaveric study was to compare torsional failure properties of bridge plating a comminuted distal fibula fracture with carbon fiber polyetheretherketone (PEEK) composite and stainless steel one-third tubular plates. "
7.	Carbon Fiber (Grafil)IBA 05/01/2016 - "Torsional Failure of Carbon Fiber Composite Plates Versus Stainless Steel Plates for Comminuted Distal Fibula Fractures." 05/01/2016 - "The objective of this cadaveric study was to compare torsional failure properties of bridge plating a comminuted distal fibula fracture with carbon fiber polyetheretherketone (PEEK) composite and stainless steel one-third tubular plates. " 05/01/2016 - "In a comminuted human fibula fracture fixation model, carbon fiber implants exhibited multiple pre-peak failures at significantly lower angles than the first failure for the stainless steel implants, with some delamination of composite layers and brittle catastrophic failure rather than plastic deformation. "
8.	TitaniumIBA 08/01/2022 - "Of those with stabilized fibula fractures, 28 (70%) were treated with a plate and 12 (30%) with a titanium elastic nail. " 05/01/2015 - "Minimal invasiveusing AO titanium elastic intramedullary nailing combined with external fixation for treatment of tibia-fibula fractures especially for the multiple-segment,long spiral mild-to-moderate comminuted with hidden fracture can get satisfactory reduction and reliable fixation,it conformes to the principle of BO completely, protects the fracture end blood supply,reduces the external fixation time, has less skin soft tissue complications, postoperative function recovered satisfactorily." 06/01/2018 - "When fibula fractures require operative fixation, implants are typically made from stainless steel or titanium alloys. "
9.	Isoflurane FDA LinkGeneric 01/01/2018 - "Rats were anesthetized using isoflurane, and ET was induced in one hindlimb via clamping retrofemoral tissues for 30 seconds, followed by closed fibula fracture. " 11/01/2020 - "Forty Wistar rats were anesthetized with isoflurane: 20 underwent bilateral hindlimb fibula fracture, soft tissue and muscular crush injury, and bone homogenate injection intended to mimic the physiological severity of bilateral femur fracture. "
10.	Opiate AlkaloidsIBA 09/01/2021 - "The odds of requiring opiates in the first 24 hours were unchanged for age above 10 years [odds ratio (OR)=0.85, 95% confidence interval (CI): 0.33-2.23], male sex (OR=1.58, 95% CI: 0.59-4.19), high-energy injury (OR=1.65, 95% CI: 0.45-6.04), presence of a fibula fracture (OR=2.21, 95% CI: 0.72-6.76), or need for fracture reduction in the ED (OR=0.57, 95% CI: 0.20-1.65). "

Therapies and Procedures

1.	External Fixators 09/01/2019 - "It remains unknown whether the SK combined external fixator (made by Double Medical Technology Inc., China) is effective for the treatment of distal metaphyseal tibia/fibula fractures in children. " 01/01/2022 - "31 patients with tibia and fibula shaft fractures who received unilateral external fixator combined with lateral auxiliary frame were included in the current study. " 01/01/2022 - "In the current study, a unilateral external fixator combined with a lateral auxiliary frame was used to treat tibia and fibula shaft fractures with poor soft tissue conditions to verify its feasibility for the ultimate treatment. " 01/01/2022 - "The Johner-Wruh scores showed that 27 cases (87.1%) were "excellent" and 4 cases (12.9%) were "good." The unilateral external fixator combined with lateral auxiliary frame is an effective option for ultimate treatment of the tibia and fibula shaft fractures with poor soft tissue conditions." 01/01/2022 - "We retrospectively analyzed the patients with tibia and fibula shaft fractures who underwent unilateral external fixator combined with lateral auxiliary frame between December 2018 and October 2020. "
2.	Therapeutics 09/01/2023 - "Matrix Rhythm Therapy (MRT) Along With Conventional Physiotherapy Proves to Be Beneficial in a Patient With Post-Operative Knee Stiffness in Case of Tibia-Fibula Fracture: A Case Report." 09/01/2013 - "Pulsed lavage therapy with a side-hole double-valve lavage tube can improve the efficacy of treatment infections after tibia/fibula fractures and constitutes an effective modification to conventional lavage techniques. " 01/01/2007 - "We present a patient with an exceptional fracture type--a Maisonneuve fracture associated with a lateral ankle fracture--and the therapy of this injury. " 01/01/1999 - "Key words: Maisonneuve fracture, fracture-dislocation of ankle, therapy, diagnosis." 02/01/2016 - "To our knowledge, this is the first reported case of bilateral distal fibula fractures in a patient on long-term bisphosphonate therapy. "
3.	Intramedullary Fracture Fixation 02/01/2006 - "Evaluate whether supplementary fibular fixation helped maintain axial alignment in distal metaphyseal tibia-fibula fractures treated by locked intramedullary nailing. " 07/01/2017 - "The aim of this study was to compare solitary tibial diaphysis fractures and tibial diaphysis fractures associated with fibula fracture treated with the intramedullary nailing method. " 07/01/2023 - "This case report documents the surgical treatment of a displaced distal fibula fracture using minimally invasive intramedullary nailing of the fibula. " 07/01/2023 - "Repair of Distal Fibula Fractures with Minimally Invasive Intramedullary Nailing in the Elderly." 10/01/2022 - "Locked intramedullary nailing provides superior functional outcomes and lower complication rates than plate fixation of distal fibula fractures. "
4.	Catheters 08/09/2010 - "Significant (P < 0.05) independent factors associated negatively with limb salvage were combined tibia and fibula fracture, concomitant artery and vein injury, ligation of venous injury, and lack of backflow after Fogarty catheter thrombectomy, while repair of popliteal artery and vein injury, when present, was associated with improved early limb salvage. "
5.	Limb Salvage 08/09/2010 - "Significant (P < 0.05) independent factors associated negatively with limb salvage were combined tibia and fibula fracture, concomitant artery and vein injury, ligation of venous injury, and lack of backflow after Fogarty catheter thrombectomy, while repair of popliteal artery and vein injury, when present, was associated with improved early limb salvage. "