Rhinorrhea

08/01/1992 - "Seventy percent of patients treated with 42 micrograms of ipratropium bromide thought it had good or excellent effect on rhinorrhea (p less than 0.05 vs placebo); significantly more patients thought that it had improved the quality of life (p = 0.02). "
05/01/1995 - "Treatment with the ipratropium spray resulted in a 30% reduction in rhinorrhea; this reduction was significantly greater than that seen with the saline vehicle. "
08/01/1999 - "Ipratropium bromide was safe and effective in controlling rhinorrhea and diminishing the interference by rhinorrhea in school attendance, concentration on school work, and sleep. "
05/01/1997 - "Treatment with ipratropium reduced symptoms of rhinorrhea primarily in patients with PNAR. "
08/01/1992 - "Mean duration and severity of rhinorrhea was decreased in both ipratropium bromide treatment groups by comparison with placebo, with consistently greatest improvement in the group treated with ipratropium bromide 42 micrograms per nostril three times a day. "

12/01/2023 - "Compared with a placebo, IB nasal spray is both safe and effective in treating the rhinorrhea associated with NAR. "
05/01/1995 - "The purpose of this study was to compare the efficacy and safety of three doses of IB nasal spray versus either vehicle or no treatment in relieving rhinorrhea in patients with naturally acquired colds. "
05/01/1995 - "Compared with either vehicle or no treatment, IB nasal spray produced a significant decrease in the severity of rhinorrhea. "
07/01/2022 - "The pharmacokinetic, safety, and tolerability profiles of 101BHG-D01 nasal spray indicate that it is a good candidate for further development as a treatment for rhinorrhea in rhinitis."
05/01/1995 - "The use of IB nasal spray appears to be a rational and safe approach to relieving rhinorrhea associated with the common cold."

08/01/2011 - "Many clinical studies and several meta-analyses conclusively demonstrate that, in addition to being safe and well-tolerated, INS are more effective than other agents (including oral and intranasal antihistamines) across the spectrum of AR symptoms, including rhinorrhea and nasal congestion."
01/01/2014 - "Antihistamines reduce nasal itch, sneeze and rhinorrhea and can be used orally or topically. "
03/01/1988 - "There were less symptoms of runny nose and itchy eyes in the active-treatment group (p less than 0.05) and also less antihistamine, p less than 0.004. "
10/01/2014 - "The results of meta-analysis showed that the efficacy of intranasal antihistamine group was superior to the placebo group in total nasal symptom scores (TNSS), the difference was significant[WMD = -1.96, 95%CI (-2.06;-1.85), P < 0.01], and individual nasal symptom scores (blocked nose, rhinorrhea, and sneezing) [WMD = -0.18, 95%CI (-0.28;-0.08); WMD = -0.45, 95%CI (-0.52;-0.38); WMD = -0.41, 95%CI (-0.58;-0.24), all P < 0.01], with significant differences. "
12/01/1998 - "The effectiveness of antihistamines in reducing the severity of runny nose and sneezing: a meta-analysis."

11/01/1990 - "Anticholinergic drugs are safe and effective for rhinorrhea. "
03/01/2010 - "However, in patients whose predominant symptom is rhinorrhea, use of atopical anticholinergic agents can be quite useful. "
11/01/1980 - "Anticholinergics have occasionally been recommended to reduce rhinorrhea, but little data on their efficacy are available."
12/01/1992 - "Intranasal anticholinergic therapy of rhinorrhea."
08/15/2009 - "Anticholinergic drugs are useful for the treatment of anterior rhinorrhea associated with allergic and nonallergic rhinitis."

07/01/2000 - "Azelastine is effective in reducing rhinorrhea and improving sleep quality. "
08/01/1994 - "Patients treated with azelastine had superior mean percent improvements in the total symptom complex score (nose blows, sneezes, stuffy nose, runny nose, itchy nose, and itchy eyes/ears/throat) versus placebo at each evaluation point and overall across all 8 weeks (P < .01) of the trial. "
12/01/2019 - "To our knowledge there are no previous descriptions in the literature that recommend azelastine to manage symptoms of rhinorrhea caused by treatments for AD. "
07/01/2000 - "The analysis of the Rhinitis Severity Score showed significant improvement only of rhinorrhea in the azelastine group (P = .03). "
02/14/1997 - "In conclusion, azelastine has been shown to be effective in the treatment of perennial rhinitis in children aged 5-12 years and to be superior to placebo in the relief of all symptoms assessed, namely sneezing, nasal blockage, nasal itch and rhinorrhea."

10/01/1998 - "Following treatment, the reductions in mean combined and individual nasal symptom scores from baseline values were significantly greater in the budesonide group compared with the placebo group (P < .0001 for all variables except runny nose P = .01). "
08/01/1995 - "There were significantly fewer reports of blocked nose (P = 0.004), runny nose (P = 0.0005) and sore eyes (P = 0.047) during budesonide treatment compared with BDP. "
12/01/1994 - "Both treatment groups reported reduced scores for runny nose and eye symptoms; no statistically significant difference was observed between budesonide and DSCG. "
08/01/1992 - "After 4 weeks, blocked nose and runny nose remained significantly less troublesome in the budesonide group. "
12/01/1994 - "Budesonide treatment produced significantly lower mean symptom scores for the whole study compared with BDP for runny nose, itchy nose and sneezing (P < 0.05). "

01/01/2005 - "The control of sneezing and rhinorrhea was comparable in both groups with a marginal advantage of montelukast. "
03/01/2004 - "Montelukast significantly improved daytime nasal symptoms score and individual scores of congestion, rhinorrhea, itching, and sneezing compared with placebo. "
12/01/2005 - "Other end points that showed statistically significant improvement with montelukast treatment were nighttime symptoms and each of the 4 nasal symptoms (congestion, rhinorrhea, sneezing, and itching). "
10/01/2005 - "FPANS added to FSC resulted in superior outcomes for daytime total nasal symptom scores (D-TNSS) and individual daytime nasal specific symptoms (congestion, rhinorrhea, sneezing, and itching) compared with montelukast plus FSC and placebo plus FSC (p < or = 0.001). "
03/01/2004 - "Montelukast plus cetirizine were more effective than cetirizine alone in preventing eye itching, rhinorrhea, and nasal itching. "

01/01/2018 - "All secondary endpoints were in favor and confirmatory of cetirizine efficacy with significant improvement in chemosis, eyelid swelling, tearing, ciliary redness, and episcleral redness, as well as nasal symptoms (rhinorrhea, nasal pruritus, ear or palatal pruritus, and nasal congestion) post-CAC. "
11/01/2019 - "Mean age of study participant was 26 ± 16.64 months and mean body weight was 10.1 ± 3.26 Kg. More than 95% cases have shown significant improvement in their baseline symptoms (rhinorrhea, sneezing, nasal blocking, coughing, feeding difficulties and sleeping difficulties) in both intervention (L-33 Probiotic) and control (Cetirizine) groups. "
07/01/2015 - "The TNSS was the sum of the four individual nasal congestion, nasal itching, rhinorrhea, and sneezing scores, in which each symptom was scored on a scale of 0 to 3. Both FPNS and cetirizine improved the primary end point when compared with placebo during the active treatment period. "
06/01/1999 - "Patients were treated for 30 days with oral cetirizine (10 mg once a day) and had to report the severity of the symptoms considered (sneezing, runny nose, itching and congestion) on daily card. "
03/01/1991 - "Patient and physician efficacy ratings corresponded, indicating superiority of cetirizine to placebo (P less than .05) in reducing symptom severity scores for sneezing, rhinorrhea, ocular pruritus, nasal pruritus, watering of the eyes, and redness of the eyes. "

08/01/2011 - "A review of the clinical studies assessing the efficacy of intranasal corticosteroids (INS) for rhinorrhea is presented. "
11/01/2007 - "Rhinorrhea not responding to nasal corticosteroids."
02/01/2015 - "The results of meta-analyses showed that the efficacy of nasal corticosteroids plus LTRA was superior to nasal corticosteroids alone in total nasal symptom scores and individual nasal symptom scores (rhinorrhea, sneezing) [WMD = -4.49, 95% CI (-4.95(-)-4.03)-, P < 0.01; WMD = -0.43, 95% CI (-0.78(-)-0.07), P < 0.05; WMD = -0.10, 95% CI (-0.6(-)-0. "
11/01/2007 - "A woman with multiple illnesses including allergic rhinitis presented for a follow-up visit at our clinic with constant rhinorrhea for 2 weeks despite regular use of nasal corticosteroids. "
11/01/1995 - "When given intranasally to relieve the sneezing, congestion, and rhinorrhea associated with seasonal and perennial allergic rhinitis, the newer corticosteroids have proved safe and effective. "

01/01/2002 - "Two studies found a significant benefit for antibiotics compared with placebo for runny nose (clear) odds ratio 0.42 (0.22-0.78). "
01/01/2000 - "One study found a significant benefit for antibiotics compared with placebo for runny nose (clear or purulent). "
11/24/2022 - "These factors, not including the absence of rhinorrhea, were associated with a longer duration of antibiotics treatment in children aged 5-17 years. "
12/14/2021 - "Children who coughed for 1-2 weeks (OR 1.73, 95% CI 1.03 to 2.90) or 3-4 weeks (OR 2.39, 95% CI 1.08 to 4.97), with runny nose (OR 1.86, 95% CI 1.13 to 3.19) or those whose family annual income between ¥50 000 and ¥100 000 (OR 4.44, 95% CI 1.52 to 18.95) had a higher risk of non-prescription use of antibiotics than those coughing for <1 week, without runny nose or with family annual income <¥50 000. "
08/01/2020 - "The most common symptom and reason to take antibiotics without a prescription was runny nose (80%-8/10) and convenience (70%-7/10) respectively. "

07/01/1992 - "We conclude that IB is a safe and effective therapy for control of rhinorrhea associated with NAPR."
09/01/2012 - "The patient initially managed with medical therapy needed a lumbar-peritoneal derivation that satisfactorily cured her rhinorrhea"
01/01/2018 - "Manifestations of rhinorrhea after therapy decreased in the group of 1A 2.0 times, and in the group of 2A 1.7 times, which was regarded as' a slight manifestation of the symptom', whereas in the groups of 1B and 2B only a tendency to improve was revealed. "
10/01/1957 - "[Present state of the problem of rhinorrhea aquosa, with special regard to its therapy]."
12/01/2019 - "Three did not initiate therapy due to excessive out-of-pocket cost, three discontinued therapy after two injections because of intolerable side effects (rhinorrhea), with the remaining 70 patients starting and continuing therapy, long-term. "

06/01/2012 - "Nasal blocking, sneeze, rhinorrhea and nasal itch were significantly improved after 3 years treatment (before treatment: 2[2;3], 2[2;3], 2[2;3], 2[1;2] ; after treatment: all were 0[0;0]; Z value were -8.310, -8.408, -8.377, -8.287, all P were 0.000). "
04/01/2021 - "The percentage of difference value of IFN-γ before and after treatment was correlated with the percentage of difference value of VAS score / rhinorrhea / sneeze / total nasal symptom score. "
03/01/2021 - "Nasal congestion and rhinorrhea were evaluated at baseline, first and second weeks after treatment. "
11/16/2013 - "After treatment, rhinorrhea was clearly reduced. "
03/01/1995 - "However, some patients have continous rhinorrhea even though the provocation test after treatment was negative. "

03/01/2002 - "A total of 154 specimens from patients with otorrhea or rhinorrhea were investigated for cerebrospinal fluid (CSF) by use of a laser-nephelometric assay for beta-TP. "
06/01/2001 - "At the end of the study, the laser group reported a more significantly improved nasal airway (91% against 75%) and decreased rhinorrhea (72.7% against 35%) when compared to the diathermy group."
02/01/2022 - "This study demonstrated that both laser and bipolar cautery are effective in improving nasal obstruction and rhinorrhea. "
09/01/2008 - "The laser group in alleviation of cough, nasal obstruction, rhinorrhea, sputum sound were significantly better than the medication group (P < 0.001, P < 0.01); the cured rate was 68.5% in the laser group and 42.4% in the medication group, the former being better than the latter (P < 0.001). "
05/01/2013 - "The symptoms were scored with four parameters (nasal obstruction, rhinorrhea, sneezing and itching) before and after illumination of the laser, and the total score was recorded. "

09/01/2007 - "A significant improvement in total symptom scores, combining sneezing, rhinorrhea and nasal obstruction, was observed after oral administration of TE for 8 weeks (P < 0.01). "
07/27/2021 - "Four weeks after oral administration of clarithromycin, significant improvement was observed in subjective symptoms including nasal congestion, rhinorrhea, postnasal drip, and general discomfort, as well as endoscopic findings including general surgical cavity condition, rhinedema, and rhinorrhea (P < .05). "
02/25/1999 - "Its efficiency in inhibition of microvascular permeability was assessed in two rhinitis models; ovalbumin and capsaicin-induced rhinorrhea could be prevented after topical application of submicromolar concentrations of 45 (IC50 = 0.25 and 0.30 microM); and it also exerted significant inhibitory effect in the first test after iv and oral administration, with ID50 = 0.005 and 0.46 mg/kg."

08/01/1983 - "Most traumatic rhinorrhea ceases after a trial of conservative management. "
01/01/2017 - "One child had a postoperative rhinorrhea confirmed to be cerebrospinal fluid but this resolved on conservative treatment. "
07/01/1999 - "The leaks at the incision responded to conservative management, while rhinorrhea usually required more aggressive means of closure. "
12/01/2011 - "Although conservative treatment is effective for managing wound leaks, it is less effective in managing patients with rhinorrhea. "
01/01/2002 - "Forty consecutive adult patients were referred to an ear, nose, and throat surgeon for pain in the region of the paranasal sinus, recurrent mucopurulent rhinorrhea, and nasal congestion or obstruction for at least 3 months without any response to conservative treatment. "