Body-Weight Trajectory

A general pattern of body weight gain or loss over many years. Weight change trajectory is influenced by several determinants in children and adults.

Also Known As:

Weight Change Trajectory; Weight Gain Trajectory; Weight Loss Trajectory; Weight Trajectory; Body Weight Trajectory; Body-Weight Trajectories; Change Trajectories, Weight; Change Trajectory, Weight; Gain Trajectories, Weight; Gain Trajectory, Weight; Loss Trajectories, Weight; Loss Trajectory, Weight; Trajectories, Body-Weight; Trajectories, Weight; Trajectories, Weight Change; Trajectories, Weight Gain; Trajectories, Weight Loss; Trajectory, Body-Weight; Trajectory, Weight; Trajectory, Weight Change; Trajectory, Weight Gain; Trajectory, Weight Loss; Weight Change Trajectories; Weight Gain Trajectories; Weight Loss Trajectories; Weight Trajectories

Networked: 128 relevant articles (3 outcomes, 30 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Weight Loss (Weight Reduction)
2.	Obesity
3.	Weight Gain
4.	Breast Neoplasms (Breast Cancer)
5.	Body Weight (Weight, Body)

Experts

1.	Purnell, Jonathan Q: 3 articles (01/2022 - 01/2018)
2.	Pané, Adriana: 3 articles (09/2021 - 12/2017)
3.	Mitchell, James E: 3 articles (11/2020 - 06/2017)
4.	Wood, G Craig: 3 articles (11/2018 - 05/2012)
5.	Hoekstra, Trynke: 2 articles (01/2022 - 01/2014)
6.	Janssen, Ignace M C: 2 articles (01/2022 - 01/2022)
7.	Monpellier, Valerie M: 2 articles (01/2022 - 01/2022)
8.	Steenhuis, Ingrid H M: 2 articles (01/2022 - 01/2022)
9.	van Stralen, Maartje M: 2 articles (01/2022 - 01/2022)
10.	Courcoulas, Anita P: 2 articles (12/2021 - 01/2018)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Body-Weight Trajectory:

1.	Air Pollutants (Pollutants, Air)IBA 01/01/2023 - "This study will evaluate the associations of prenatal exposure to ambient air pollutants with weight trajectories from the 3rd trimester through age 2 years. " 11/08/2021 - "In this study, we use the air pollutants, aerosol number concentration, and meteorological elements data in Beijing, combined with the HYSPLIT model, to calculate the potential source contribution factor(PSCF) and concentration weight trajectory(CWT), and analyze the characteristics of evolution and potential source apportionment of atmospheric pollutants during the two episodes. "
2.	Biomarkers (Surrogate Marker)IBA 01/01/2021 - "These biomarkers were also associated with higher BMI at age 4. Finally, within 4 unique weight trajectories (low, normal, high, and low-high), children of mothers with higher 8-iso-PGF2α were 2.56 times more likely (95% CI 1.22, 5.41) to be in the low-high trajectory than children in the normal group. " 10/01/2020 - "maternal health-related quality of life, engagement and retention in LBC program, biochemical markers, vascular function testing, infant weight trajectory, incremental cost-effectiveness ratios. " 12/01/2017 - "To test this hypothesis, we have evaluated the association between longitudinal changes in weight trajectories, cognitive performance, AD biomarker profiles and brain structure in 363 healthy controls from the Alzheimer´s Disease Neuroimaging Initiative (mean follow-up 50.5±30.5 months). " 01/01/2022 - "Changes in insulin resistance and beta-cell function biomarkers are distinct but related correlates of weight trajectory groups that evolve contemporaneously over time. " 01/01/2022 - "Overall, weight trajectory groups have been shown to differ by age of onset, sex, and patterns of insulin resistance or beta-cell function biomarkers. "
3.	LeptinIBA 03/30/2022 - "Leptin Levels of the Perinatal Period Shape Offspring's Weight Trajectories through the First Year of Age." 01/01/2018 - "Here, we compared basal and stimulated leptin levels in relation to cardiometabolic risk and weight trajectories in black and white subjects. " 01/01/2018 - "Basal and Dynamic Leptin Secretion: Association with Cardiometabolic Risk and Body Weight Trajectories in African-Americans and European-Americans." 01/01/2021 - "Adiponectin and leptin gene variants and their effects on body weight trajectories in children from birth to 6 years of age: the PREDI Study."
4.	Insulin (Novolin)FDA Link 10/01/2019 - "Long-term body weight trajectories and metabolic control in type 1 diabetes patients on insulin pump or multiple daily injections: A 10-year retrospective controlled study." 12/01/2013 - "Maternal insulin resistance, triglycerides and cord blood insulin in relation to post-natal weight trajectories and body composition in the offspring up to 2 years." 09/01/2014 - "Using latent class trajectory analysis, we identified different weight gain trajectories in six age and sex strata, and used multivariable general linear mixed effects models to assess elevated metabolic markers of diabetes (fasting glucose, HbA1c, HOMA-IR, insulin) across weight trajectory classes. "
5.	AdiponectinIBA 04/01/2012 - "Human milk adiponectin affects infant weight trajectory during the second year of life." 01/01/2021 - "Adiponectin and leptin gene variants and their effects on body weight trajectories in children from birth to 6 years of age: the PREDI Study."
6.	Proteins (Proteins, Gene)FDA Link 01/01/2018 - "The aim of this study was to directly compare the effect of protein from 2 common complementary food sources, meat and dairy, on infant growth and weight trajectory. " 02/01/2015 - "Pretreatment percentage protein intake was not associated with weight trajectories. "
7.	LipidsIBA 10/01/2023 - "This study identified the effect of maternal stature, weight status, and blood lipid profiles during pregnancy on postnatal weight trajectories of the twin offspring, thereby providing a basis for twin pregnancy management to improve the long-term health of the offspring." 10/01/2023 - "Maternal weight, blood lipids, and the offspring weight trajectories during infancy and early childhood in twin pregnancies." 01/01/2020 - "Our objectives were: 1) to characterize maternal weight trajectories from 1 to 24 mo postpartum, 2) to determine the association of prepregnancy BMI, gestational weight gain (GWG), and pregnancy behaviors with the trajectories, and 3) to evaluate the association of weight trajectories with BMI, waist circumference (WC), lipid profile, glucose, insulin resistance, blood pressure, and inflammatory markers at 3 y postpartum. "
8.	Hormones (Hormone)IBA 06/01/2001 - "The long-term, total body weight trajectory at mid-life is not influenced appreciably by either cessation of ovarian function or by hormone replacement." 01/01/2018 - "This study investigates weight trajectories in pre- versus postmenopausal breast cancer (BC) survivors diagnosed with hormone receptor-positive tumors, with a specific focus on discerning menopausal status and type of endocrine treatment (ET) as risk factors for weight gain during ET. "
9.	AerosolsIBA 09/08/2021 - "Based on hourly concentration data of PM10 and PM2.5 from 2017 to 2019 and wind speed and direction data at the corresponding times in Yangquan, an urban valley of the Taihang Mountains, the characteristics of air transport in a cross-valley urban area and their influence on aerosols in Yangquan were analyzed using the HYSPLIT model, cluster analysis, and the potential source contribution factor and concentration weight trajectory methods. " 11/08/2021 - "In this study, we use the air pollutants, aerosol number concentration, and meteorological elements data in Beijing, combined with the HYSPLIT model, to calculate the potential source contribution factor(PSCF) and concentration weight trajectory(CWT), and analyze the characteristics of evolution and potential source apportionment of atmospheric pollutants during the two episodes. "
10.	Endocrine DisruptorsIBA 01/01/2021 - "Prenatal exposures to mixtures of endocrine disrupting chemicals and children's weight trajectory up to age 5.5 in the SELMA study."

Therapies and Procedures

1.	Gastrectomy 01/01/2020 - "Economic evaluation of a decision analytic model comparing the outcomes of the standard care in Canada with an improved bariatric care pathway with earlier sleeve gastrectomy delivery and better postsurgical weight trajectory. " 01/01/2020 - "Modeling weight trajectory after sleeve gastrectomy and resolution rates for comorbidities in Canada in comparison with an improved care pathway to estimate differences in patient-years of comorbidity treatment over 10 years following referral and the associated costs. " 01/01/2013 - "There may be hormonal mediators involved in determining the weight trajectory following sleeve gastrectomy, though the extremely limited data currently available prohibits definitive conclusions from being drawn. " 10/01/2017 - "Patients who underwent Roux-en-Y gastric bypass or sleeve gastrectomy at our tertiary academic hospital from August 2008 to August 2012 were mailed a survey, from which weight trajectory and PBSH symptoms were assessed. " 11/01/2020 - "The following is a methods and design description for a prospective, 24-month longitudinal study of 144 bariatric surgery patients, at 2 sites, that aimed to identify predictors of weight loss trajectories over 24 months after Roux-en-Y gastric bypass and the sleeve gastrectomy. "
2.	Prenatal Care (Care, Prenatal) 11/01/2015 - "CP+ was associated with improved weight trajectories compared with controls (P < .0001): women at clinical sites randomized to group prenatal care gained less weight during pregnancy and lost more weight postpartum. " 10/20/2023 - "Data from 989 women were examined for weight trajectories from first antenatal care visit in pregnancy to 12 months postpartum using latent-class growth models. " 10/01/2023 - "The objective was to identify patterns of systolic blood pressure (SPB) trajectory in pregnant women undergoing prenatal care at the Unified Health System, and associations with weight gain trajectory, demographic, obstetric, anthropometric data, and health related behaviors. " 11/01/2015 - "Group prenatal care has a significant impact on weight gain trajectories in pregnancy and postpartum. " 11/01/2015 - "Women with the highest levels of depression and prenatal distress exhibited the greatest positive impact of group prenatal care on weight trajectories during pregnancy and through 12 months postpartum. "
3.	Length of Stay 12/14/2021 - "A lack of perceived improved weight gain trajectory for those in the FICare group is attributed to a shorter length of hospital stay and infants being discharged prior to regaining BW."
4.	Bariatric Surgery 10/01/2023 - "Development and validation of an interpretable machine learning-based calculator for predicting 5-year weight trajectories after bariatric surgery: a multinational retrospective cohort SOPHIA study." 09/01/2023 - "To conduct a systematic review to summarize the results of studies on this subject and to identify whether single nucleotide polymorphisms (SNPs) are good prognostic markers for body weight trajectory after bariatric surgery. " 01/01/2022 - "This study distinguishes demographic and behavioral factors that may influence long-term weight loss trajectories after bariatric surgery. " 11/01/2020 - "Comment on: Identifying mechanisms that predict weight trajectory after bariatric surgery: rationale and design of the BioBehavioral Trial." 11/01/2020 - "Identifying mechanisms that predict weight trajectory after bariatric surgery: rationale and design of the biobehavioral trial."
5.	Gastric Bypass (Roux-en-Y Gastric Bypass) 11/01/2018 - "This study evaluated the weight trajectories of Roux-en-Y gastric bypass (RYGB) patients and identified the distinct clinical, behavioral, and demographic features of patients by trajectory. " 10/01/2023 - "A weight loss trajectory is at least as effective without additional preparation in terms of 2 years postoperative %TWL for primary gastric bypass and sleeve procedures. " 01/01/2022 - "To examine long-term weight trajectory in patients undergoing Roux-en-Y gastric bypass (RYGB) and determine factors predicting long-term follow-up and weight outcomes. " 03/09/2020 - "This was a monocentric retrospective study with calculation of the weight trajectory of patients having undergone gastric bypass surgery. " 11/01/2018 - "Demographic, clinical, and behavioral determinants of 7-year weight change trajectories in Roux-en-Y gastric bypass patients."