Agent Orange

A herbicide that contains equal parts of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), as well as traces of the contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Also Known As:

(2,4-dichlorophenoxy)acetic acid, butyl ester, mixt. with butyl (2,4,5-trichlorophenoxy)acetate; 2,4-D - 2,4,5-T mixture; Orange, Agent; (2,4,5-Trichlorophenoxy)acetic acid - (2,4-dichlorophenoxy)acetic acid (1:1)

Networked: 159 relevant articles (1 outcomes, 24 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Terris, Martha K: 5 articles (07/2015 - 01/2006)
2.	Michalek, Joel E: 3 articles (01/2020 - 09/2004)
3.	Amling, Christopher L: 3 articles (07/2015 - 05/2009)
4.	Aronson, William J: 3 articles (07/2015 - 05/2009)
5.	Freedland, Stephen J: 3 articles (07/2015 - 05/2009)
6.	Kane, Christopher J: 3 articles (07/2015 - 05/2009)
7.	Ohrr, Heechoul: 3 articles (12/2014 - 09/2013)
8.	Yi, Sang-Wook: 3 articles (12/2014 - 09/2013)
9.	Schecter, Arnold: 3 articles (07/2009 - 04/2005)
10.	Kojadinovic, Arsenije: 2 articles (02/2022 - 01/2021)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "Agent Orange exposure was associated with improved 10-year overall survival in upper aerodigestive tract cancer patients. " 12/01/2014 - "To the authors' knowledge, few studies to date have examined the association between Agent Orange exposure and cancer incidence among Korean veterans who were exposed to Agent Orange during the Vietnam War. " 05/01/2003 - "Since the Vietnam War ended in 1975, numerous studies have been conducted to determine if an association exists between Agent Orange exposure and certain disabling conditions specifically cancer. " 08/01/1997 - "Because of concerns among veterans over Agent Orange exposure, the Department of Veterans Affairs (VA) has conducted a series of studies of specific cancers among Vietnam veterans. " 06/29/1984 - "5n accordance with the requirements of the Privacy Act, the Public Health Service (PHS) is publishing notice of a proposal to establish a new Privacy Act system of records: 09-20-0162, "Records of Subjects in Agent Orange, Vietnam Experience, and Selected Cancers Studies, HHS/CDC/CEH." We are also proposing routine uses for this system. "
2.	Thyroid Neoplasms (Thyroid Cancer) 01/01/2023 - "Two studies investigating Agent Orange exposure among United States Vietnam War veterans found a significant risk of thyroid cancer following exposure. " 01/01/2016 - "The aim of this study was to further understand the characteristics of thyroid cancer patients in the VHA population, particularly in relation to Agent Orange exposure. " 01/01/2016 - "Thyroid cancer patients, in this sample, have a higher prevalence of self-reported Agent Orange exposure compared to the overall national VA patient population. " 01/01/2016 - "There was a significantly higher proportion of self-reported Agent Orange exposure among thyroid cancer patients (10.0%), compared to the general VHA population (6.2%) (P<.0001). " 01/01/2016 - "HIGH PREVALENCE OF AGENT ORANGE EXPOSURE AMONG THYROID CANCER PATIENTS IN THE NATIONAL VA HEALTHCARE SYSTEM."
3.	Prostatic Neoplasms (Prostate Cancer) 04/01/2016 - "Most studies on the relationship between Agent Orange and prostate cancer have focused on US veterans of the Vietnam War. " 06/16/2023 - "Agent Orange exposure and prostate cancer risk in the Million Veteran Program." 01/01/2021 - "It is unknown if Agent Orange (AO)-exposed veterans have worse outcomes than unexposed Veterans after prostate cancer treatment. " 01/01/2021 - "The Stage at Presentation and Oncologic Outcomes for Agent Orange Exposed and Non-Exposed United States Veterans Diagnosed With Prostate Cancer." 10/01/2020 - "A subset of the veteran population was also exposed to Agent Orange, which has been shown to increase the incidence of aggressive forms of prostate cancer. "
4.	Congenital Abnormalities (Deformity) 10/01/2006 - "The summary relative risk (RR) of birth defects associated with exposure to Agent Orange was 1.95 [95% confidence interval (95% CI) 1.59-2.39], with substantial heterogeneity across studies. " 04/01/2022 - "Exposures to Agent Orange were initially linked to birth defects among Vietnamese civilians residing near aerially sprayed regions. " 05/01/2009 - "Does paternal exposure to Agent Orange cause birth defects?" 10/01/2006 - "Commentary: Agent Orange and birth defects in Vietnam." 10/01/2006 - "Parental exposure to Agent Orange appears to be associated with an increased risk of birth defects."
5.	Sarcoma (Soft Tissue Sarcoma) 11/01/2003 - "'Proximal-type' epithelioid sarcoma: is Agent Orange still at large?" 12/01/1990 - "Several attributes of military service in Vietnam (eg, branch, duration of service, military region, and other characteristics that may have been associated with the use of Agent Orange) were examined, and none was associated with an increased risk for the development of sarcoma. " 05/06/1982 - "Thoracic soft-tissue sarcoma in Vietnam veterans exposed to Agent Orange." 04/01/1998 - "Exposure to Agent Orange and occurrence of soft-tissue sarcomas or non-Hodgkin lymphomas: an ongoing study in Vietnam." 06/01/2010 - "Although Agent Orange has been associated with soft-tissue sarcoma, an association with desmoplastic small round-cell tumor has not been reported. "

Related Drugs and Biologics

1.	Herbicides
2.	Polychlorinated Dibenzodioxins (TCDD)
3.	Dioxins
4.	Prostate-Specific Antigen (Semenogelase)
5.	Androgens
6.	Adrenal Cortex Hormones (Corticosteroids)
7.	Carcinogens
8.	Pesticides
9.	Amyloid beta-Peptides
10.	Insulin (Novolin)

Related Therapies and Procedures

1.	Therapeutics
2.	Prostatectomy (Retropubic Prostatectomy)
3.	Breast Implants (Breast Implant)
4.	Segmental Mastectomy (Lumpectomy)
5.	Surgical Amputation (Amputations)