A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
Also Known As:
CYP46A1; 5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase; Brain-Specific 24S-Hydroxylase; Cholestane Tetrol 24-Hydroxylase; Cytochrome P450 46A1; Brain Specific 24S Hydroxylase; Cholestane Tetrol 24 Hydroxylase; Cholesterol 24 Hydroxylase