Sequestosome-1 Protein
A multidomain protein that is highly conserved among multicellular organisms. It contains a ZZ-type ZINC FINGER domain, C-terminal UBIQUITIN - associated (UBA) domain, and interacts with many other signaling proteins and enzymes including, atypical PROTEIN KINASE C; TNF RECEPTOR-ASSOCIATED FACTOR 6; subunits of the mTORC1 complex, and CASPASE-8. It functions in AUTOPHAGY as a receptor for the degradation of ubiquitinated substrates, and to co-ordinate signaling in response to OXIDATIVE STRESS.
Also Known As:
EBI3-Associated Protein of 60 KDa; EBIAP Protein; Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 Kda; Ubiquitin-Binding Protein p62; EBI3 Associated Protein of 60 KDa; Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62 Kda; Sequestosome 1 Protein; Ubiquitin Binding Protein p62
Networked: 18
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Alafuzoff, Irina:
3 articles
(12/2011 - 04/2008)
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2. | Hartikainen, Päivi:
3 articles
(12/2011 - 04/2008)
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3. | Pikkarainen, Maria:
3 articles
(12/2011 - 04/2008)
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4. | Decheng, Bai:
1 article
(01/2022)
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5. | Lixia, Zhao:
1 article
(01/2022)
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6. | Wei, Sun:
1 article
(01/2022)
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7. | Duan, Ning:
1 article
(06/2018)
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8. | Hu, Bin:
1 article
(06/2018)
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9. | Li, Ming:
1 article
(06/2018)
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10. | Li, Zhong:
1 article
(06/2018)
|
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