Mometasone Furoate (Nasonex)

A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.

Also Known As:

Nasonex; Elocon; Asmanex; Asmanex Twisthaler; Mometasone; Mometasone Furoate Monohydrate; Rinelon; Sch 32088; Sch-32088; Furoate Monohydrate, Mometasone; Furoate, Mometasone; Monohydrate, Mometasone Furoate; Sch32088; Twisthaler, Asmanex

Networked: 598 relevant articles (129 outcomes, 213 trials/studies)

Relationship Network

Drug Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnadienes
        Pregnadienediols
        Mometasone Furoate: 598
        Formoterol Fumarate Drug Combination Mometasone Furoate: 2
        indacaterol acetate-mometasone furoate drug combination

Experts

1.	Meltzer, Eli O: 16 articles (03/2014 - 09/2002)
2.	Gates, Davis: 15 articles (01/2020 - 01/2008)
3.	Staudinger, Heribert: 15 articles (11/2013 - 08/2005)
4.	Tillmann, Hanns-Christian: 11 articles (06/2022 - 01/2020)
5.	Shekar, Tulin: 11 articles (01/2020 - 06/2010)
6.	Nolte, Hendrik: 10 articles (09/2014 - 07/2010)
7.	Teper, Ariel: 9 articles (11/2013 - 05/2009)
8.	Navaratnam, Prakash: 9 articles (07/2012 - 12/2009)
9.	Vaidya, Soniya: 8 articles (06/2022 - 05/2015)
10.	Hosoe, Motoi: 8 articles (05/2022 - 01/2020)

Related Diseases

1.	Asthma (Bronchial Asthma) 01/01/2001 - "Mometasone furoate 200 microg twice daily or 400 microg once daily in the morning or 200 microg once daily in the evening improved lung function, asthma symptom scores and use of rescue medication to a significantly greater extent than placebo in patients who had previously received only short-acting inhaled beta2-adrenoceptor agonists alone as treatment in 3 trials (n = 195 to 306). " 11/01/2006 - "Both mometasone furoate DPI doses were well tolerated and significantly improved lung function, maintained effective asthma control, and improved quality of life in children with asthma." 01/01/2006 - "Inhaled mometasone furoate is equally effective in controlling asthma when administered in two divided doses or as a single daily dose. " 09/01/2000 - "Mometasone furoate administered once daily is as effective as twice-daily administration for treatment of mild-to-moderate persistent asthma." 10/01/2021 - "Mometasone furoate may be effective and safe for paediatric asthma."
2.	Allergic Rhinitis 11/07/2005 - "The results indicated that mometasone is effective in allergic rhinitis, not only during the period of application, but also after the interruption of application." 07/20/2022 - "In order to evaluate the efficacy of intranasal mometasone furoate in patients with non-allergic rhinitis (NAR), a real-life, observational, prospective study is performed. " 07/20/2022 - "Mometasone Furoate in Non-Allergic Rhinitis: A Real-Life Italian Study." 09/01/2016 - "Mometasone furoate in the treatment of mild, moderate, or severe persistent allergic rhinitis: a non-inferiority study (PUMA)." 12/01/2022 - "To evaluate the effect of intranasal mometasone furoate (INMF) on short-term intraocular pressure (IOP) alterations in children with allergic rhinitis (AR). "
3.	Seasonal Allergic Rhinitis (Hay Fever) 06/01/2012 - "Early interventional treatment with intranasal mometasone furoate in Japanese cedar/cypress pollinosis: a randomized placebo-controlled trial." 05/01/2012 - "Effects of intranasal mometasone furoate on itchy ear and palate in patients with seasonal allergic rhinitis." 01/01/2010 - "Mometasone furoate improves nasal and ocular symptoms of seasonal allergic rhinitis in adolescents." 07/01/2009 - "Mometasone furoate improves nasal and ocular symptoms of seasonal allergic rhinitis in adolescents." 01/01/2008 - "Intranasal mometasone furoate alleviates the ocular symptoms associated with seasonal allergic rhinitis: results of a post hoc analysis."
4.	Nasal Obstruction 06/01/2012 - "This study aims to evaluate the effects of topical mometasone treatment on symptoms and size of adenoid tissue in children with complaints of nasal obstruction and to compare this approach to continuous nasal saline douching plus environmental control alone. " 07/16/2008 - "The third randomized, parallel-group trial showed that 77.7% of patients treated with mometasone (100 micrograms/day) for 40 days demonstrated an improvement in nasal obstruction symptoms and a decrease in adenoid size, such that adenoidectomy could be avoided, whereas no significant improvement was observed in the placebo group. " 03/01/2010 - "After ineffective revision sinus surgery and prolonged mometasone furoate application, 19 consecutive mild and moderate NP patients suffering from nasal obstruction (NO) and olfactory dysfunction (OD) were prospectively entered into the study to undergo DLPE under topical anesthesia. " 05/01/2020 - "This case series summarizes superiority of using intranasal mometasone furoate spray (IMS) and continuous positive airway pressure (CPAP) to treat nasal obstruction in neonates with MNS. " 10/01/2015 - "Mometasone has been reported to improve the symptoms of nasal obstruction in children with adenoidal hypertrophy. "
5.	Dermatitis 08/01/2014 - "The aim of this study was to develop a new stable gel containing mometasone furoate (MF), with anti-inflammatory activity and a controlled delivery, to improve topical treatment of scalp dermatitis. " 10/01/2011 - "In the recently published Phase III N06C4 trial of mometasone cream vs. placebo to prevent radiation dermatitis, the primary provider-assessed (PA) endpoint, using the Common Toxicity Criteria for Adverse Events (CTCAE), was negative. " 06/01/2001 - "The aim of this study was to investigate the effect of mometasone furoate cream (MMF) on radiation dermatitis in a prospective, double-blind, randomized study. " 03/15/2015 - "Erratum to: Hindley A, Zain Z, Wood L, et al. Mometasone furoate cream reduces acute radiation dermatitis in patients receiving breast radiation therapy: results of a randomized trial. " 11/15/2014 - "Mometasone furoate cream reduces acute radiation dermatitis in patients receiving breast radiation therapy: results of a randomized trial."

Related Drugs and Biologics

1.	Nasal Sprays
2.	Adrenal Cortex Hormones (Corticosteroids)
3.	Steroids
4.	indacaterol
5.	Glycopyrrolate (Glycopyrronium Bromide)
6.	Clobetasol (Clobetasol Propionate)
7.	Fluticasone (Cutivate)
8.	Mometasone Furoate (Nasonex)
9.	Ointments (Pastes)
10.	Iridium

Related Therapies and Procedures

1.	Therapeutics
2.	Dry Powder Inhalers
3.	Nebulizers and Vaporizers (Inhaler)
4.	Stents
5.	Adenoidectomy