Hoarding Disorder

Disordered behavior associated with clinically significant distress or impairment in social, occupational or other important areas of functioning and persistent difficulty parting with possessions due to a perceived need to save the items and distress associated with discarding them. (from DSM-V) The quantity of collected items sets the behavior apart from normal collecting behaviors.

Also Known As:

Networked: 42 relevant articles (5 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Body Dysmorphic Disorders (Body Dysmorphic Disorder)
2.	Excoriation Disorder
3.	Trichotillomania
4.	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
5.	Psychotic Disorders (Schizoaffective Disorder)

Experts

1.	Ayers, Catherine R: 3 articles (01/2021 - 03/2014)
2.	Twamley, Elizabeth W: 3 articles (01/2021 - 03/2014)
3.	Saxena, Sanjaya: 3 articles (03/2018 - 03/2014)
4.	Biondo, Alexander Welker: 2 articles (01/2022 - 01/2020)
5.	Cunha, Graziela Ribeiro da: 2 articles (01/2022 - 01/2020)
6.	Dos Santos, Andrea Pires: 2 articles (01/2022 - 01/2020)
7.	Langoni, Hélio: 2 articles (01/2022 - 01/2020)
8.	Martins, Camila Marinelli: 2 articles (01/2022 - 01/2020)
9.	Morikawa, Vivien Midori: 2 articles (01/2022 - 01/2020)
10.	Pellizzaro, Maysa: 2 articles (01/2022 - 01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hoarding Disorder:

1.	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 09/01/2014 - "These results suggest that venlafaxine extended-release may be effective for the treatment of hoarding disorder. " 09/01/2014 - "Therefore, we conducted an open-label trial of venlafaxine extended-release for hoarding disorder. " 09/01/2014 - "Twenty-four patients fulfilling the DSM-5 criteria for hoarding disorder were treated with venlafaxine extended-release for 12 weeks. " 09/01/2014 - "Venlafaxine extended-release treatment of hoarding disorder."
2.	7,7'- dimethoxy- (4,4'- bi- 1,3- benzodioxole)- 5,5'- dicarboxylic acid dimethyl ester (BDD)IBA 01/01/2021 - "This meta-analysis aims to separately calculate the pooled prevalence rates of lifetime suicide attempts and current or lifetime suicidal ideation in BDD, Hoarding Disorder (HD), Skin Picking Disorder (SPD) and Trichotillomania (TTM) and to identify factors associated with increased suicide rates. " 01/25/2020 - "In total, 557 adults from the extant community participated by completing self-report scales that measured perceptions of adverse childhood relationships, symptoms of depression, obsessive-compulsive disorder (OCD), hoarding disorder (HD), body dysmorphic disorder (BDD), and suicidal experiences. " 01/01/2023 - "Body dysmorphic disorder (BDD), hoarding disorder (HD), skin-picking disorder (SPD), and hair-pulling disorder (HPD) are characterized by compulsive behaviours leading to distress and impairment. " 01/01/2022 - "However, the disorders grouped with OCD in the DSM-5, obsessive-compulsive and related disorders (OCRD; e.g., hoarding disorder (HD), body dysmorphic disorder (BDD), trichotillomania (TTM), excoriation disorder (ED)), have rarely been examined in the perinatal period. " 06/01/2014 - "One of these significant changes was the placement of OCD in a new category, "Obsessive-Compulsive and Related Disorders (OCRDs)," which also includes body dysmorphic disorder (BDD), trichotillomania (hair-pulling disorder), excoriation (skin-picking) disorder, hoarding disorder, substance/medication-induced OCRD, OCRD due to another medical condition, and other specified OCRDs. "
3.	AntibodiesIBA 01/01/2020 - "Accordingly, this study aimed to assess the seroprevalence of anti-Toxoplasma gondii antibodies and associated factors in individuals with animal hoarding disorder (AHD) and their dogs in Curitiba, Southern Brazil. " 01/01/2022 - "Serological survey of anti-Leptospira spp. antibodies in individuals with animal hoarding disorder and their dogs in a major city of Southern Brazil." 01/01/2020 - "Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil."
4.	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 02/01/2010 - "Although the majority of studies using serotonin-reuptake inhibitors have shown a poor response among people with hoarding disorder, serious methodological problems limit the conclusions that can be drawn from these studies. "
5.	N- (4- (beta- N'- morpholinoethoxy)phenyl)phthalimide (F63)IBA 12/01/2015 - "All patients suffered from psychiatric illnesses, mainly from addiction (F1: 41 %), psychosis (F2: 17 %), depression (F3: 17 %), and hoarding disorder (F63.8: 12 %). " 07/01/2015 - "All patients suffered from psychiatric illnesses, mainly from addiction (F1: 41%), psychosis (F2: 17%), depression (F3: 17%), and hoarding disorder (F63.8: 12%). "
6.	Methylphenidate (Ritalin)FDA LinkGeneric 06/01/2013 - "Does extended release methylphenidate help adults with hoarding disorder?: a case series."
7.	Fibrinogen (Factor I)FDA Link 01/01/2021 - "Multiple Indicators Multiple Causes (MIMIC) confirmatory bifactor analysis results showed that the OCSD general factor (i.e., obsessive-compulsive spectrum factor) was positively associated with Negative Affectivity, whereas Body Dysmorphic Disorder (BDD), Hoarding Disorder (HD), and Skin-Picking Disorder (SPD) specific factors showed significant and substantial differential relationships with dysfunctional personality domains. "
8.	Conjugated (USP) Estrogens (Premarin)FDA Link 10/01/2016 - "This last point is similar to the definition given in the DSM-5 for the Hoarding disorder which describes a persistent difficulty parting with possessions; distress associated with discarding possessions; and accumulations that congest and clutter active living areas. "
9.	ElementsIBA 01/01/2019 - "It is officially recognized as a distinct condition in DSM-5 and placed under obsessive-compulsive conditions.1 Before the designation in DSM-5, hoarding was regarded as a diagnostic element in obsessive-compulsive personality disorder or a symptom nested within obsessive-compulsive disorder (OCD).2 In DSM-5, hoarding disorder is defined by great reluctance or outright refusal to discard belongings-including articles of limited value. "
10.	Dopamine (Intropin)FDA LinkGeneric 07/01/2021 - "These behaviors range from the so-called behavioral addictions to dopamine dysregulation syndrome, punding and hoarding disorders. "

Therapies and Procedures

1.	Therapeutics 11/01/2019 - "This paper sought to assess whether cognitive analytic therapy (CAT) was effective with a male patient meeting diagnostic criteria for hoarding disorder (HD) who had been nonresponsive to two previous courses of cognitive behaviour therapy. " 01/01/2016 - "A systematic review compares the efficacy of various CBT methods, with particular attention to comparing therapy that is traditionally used to treat OCD with those designed specifically to treat hoarding disorder. " 03/01/2014 - "Targeting neurocognitive deficits in behavioral therapy for these geriatric patients with hoarding disorder doubled response rates relative to our previous trial of cognitive behavior therapy alone." 03/01/2022 - "A critical review of cognitive behavioural therapy for hoarding disorder: How can we improve outcomes?" 03/01/2020 - "Treating hoarding disorder with compassion-focused therapy: A pilot study examining treatment feasibility, acceptability, and exploring treatment effects."
2.	Cognitive Training 03/01/2014 - "Novel treatment for geriatric hoarding disorder: an open trial of cognitive rehabilitation paired with behavior therapy." 03/01/2018 - "To compare the efficacy of Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) with geriatric case management (CM) in a sample of older adults meeting DSM-5 diagnostic criteria for hoarding disorder (HD). " 01/01/2021 - "The objective of this paper was to examine the implementation and effectiveness of a community-based intervention for hoarding disorder (HD) using Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST). " 03/01/2018 - "Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) for Hoarding Disorder in Older Adults: A Randomized Clinical Trial."
3.	Activities of Daily Living (ADL) 01/01/2020 - "Hoarding disorder is a chronic and debilitating illness associated with restrictions on activities of daily living, compromised social and occupational functioning, and adverse health outcomes. " 04/01/2013 - "Activities of Daily Living Scale in Hoarding Disorder."
4.	Transcranial Magnetic Stimulation 11/01/2015 - "A case study of clinical and neuroimaging outcomes following repetitive transcranial magnetic stimulation for hoarding disorder."
5.	Drug Therapy (Chemotherapy) 01/01/2019 - "This brief review deals with the various issues that contributed to the creation of the new Diagnostic and Statistical Manual condition of hoarding disorder (HD) and attempts at reviewing its pharmacotherapy. " 01/01/2019 - "Pharmacotherapy for Hoarding Disorder: How did the Picture Change since its Excision from OCD?"