ELAV-Like Protein 2

A neural-specific RRM protein that binds to several 3'UTRs, including its own as well as that of PROTO-ONCOGENE PROTEINS C-FOS and ID DNA BINDING PROTEIN INHIBITOR. It binds through the recognition of a GAAA motif in the RNAs.

Also Known As:

ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B); ELAVL2 protein; HuB Antigen; HuB Paraneoplastic Encephalomyelitis Antigen; HuB Protein; 2, ELAV-Like Protein; Antigen, HuB; ELAV Like Protein 2; Protein 2, ELAV-Like; Protein, HuB; protein, ELAVL2

Networked: 59 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Abulajiang, Gulinaer: 2 articles (11/2020 - 02/2020)
2.	Cui, Wen-Li: 2 articles (11/2020 - 02/2020)
3.	Gao, Hai-Xia: 2 articles (11/2020 - 02/2020)
4.	Sang, Wei: 2 articles (11/2020 - 02/2020)
5.	Xue, Jing: 2 articles (11/2020 - 02/2020)
6.	Zhang, Wei: 2 articles (11/2020 - 02/2020)
7.	Uddin, Md Nazim: 1 article (05/2022)
8.	Wang, Xiaosheng: 1 article (05/2022)
9.	Chi, Pan: 1 article (01/2022)
10.	Cosgrove, Michael S: 1 article (01/2022)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2018 - "Previous studies indicate that 14-3-3ζ is a central cellular hub protein that regulates multiple signaling pathways involved in cancer progression. " 01/01/2022 - "A two-hub-protein-based risk score system might be used for predicting tumor recurrence in rectal MAC patients. " 01/01/2020 - "YWHAZ (also named 14-3-3ζ) is a central hub protein for many signal transduction pathways and plays a significant role in tumor progression. " 05/01/2019 - "Thus, CD147 serves as a hub protein in cancer, as it is involved in several homophilic and heterophilic cellular interactions spanning the major hallmarks of cancer. " 01/01/2013 - "Ras is a hub protein in signal transduction pathways leading to the control of cell proliferation, migration, and survival and a major target for drug discovery due to the presence of its mutants in about 20% of human cancers. "
2.	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 02/01/2020 - "TCL1 as a hub protein associated with the PI3K/AKT signaling pathway in diffuse large B-cell lymphoma based on proteomics methods." 02/01/2020 - "This study aimed to investigate the hub protein related to the phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT) signaling pathway in diffuse large B-cell lymphoma (DLBCL). "
3.	Kidney Diseases (Kidney Disease) 09/01/2023 - "The PPI network studies identified Matrix-metalloproteinase-9 (MMP-9) as a hub protein playing a vital role in glomerulonephritis tubular diseases and some genetic kidney diseases. "
4.	Glomerulonephritis 09/01/2023 - "The PPI network studies identified Matrix-metalloproteinase-9 (MMP-9) as a hub protein playing a vital role in glomerulonephritis tubular diseases and some genetic kidney diseases. "
5.	Mental Disorders (Mental Disorder) 01/01/2008 - "DISC1 is a hub protein in a multidimensional risk pathway for major mental illness, and studies of this pathway are opening up opportunities for a better understanding of causality and possible mechanisms of intervention."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Hepatocyte Nuclear Factor 4
3.	Proto-Oncogene Proteins c-akt (Protein Kinase B)
4.	Transcription Factors (Transcription Factor)
5.	TNF Receptor-Associated Factor 6 (TRAF6)
6.	MicroRNAs (MicroRNA)
7.	Estrogen Receptors
8.	Phosphotransferases (Kinase)
9.	Myeloid Differentiation Factor 88
10.	alpha-Synuclein

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)