compound 106

antineoplastic; structure in first source

Also Known As:

(5-((3,4-dimethylphenyl)methyl)-1-((3-methoxyphenyl)methyl)-6,7-dihydro-4H-pyrazolo(4,3-c)pyridin-3-ium-3-yl)-((3R)-3-hydroxypiperidin-1-yl)methanone

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Costa, Barbara: 1 article (01/2018)
2.	Da Settimo, Federico: 1 article (01/2018)
3.	Daniele, Simona: 1 article (01/2018)
4.	Giacomelli, Chiara: 1 article (01/2018)
5.	Giustiniano, Mariateresa: 1 article (01/2018)
6.	La Pietra, Valeria: 1 article (01/2018)
7.	La Regina, Giuseppe: 1 article (01/2018)
8.	Marinelli, Luciana: 1 article (01/2018)
9.	Martini, Claudia: 1 article (01/2018)
10.	Novellino, Ettore: 1 article (01/2018)

1.	Neoplasms (Cancer) 04/01/2014 - "Furthermore, as a single agent, compound 106 inhibits the growth of transplanted tumors, probably by inducing apoptosis in tumors. " 01/01/2018 - "Among pro-apoptotic inducers, the Bcl-2 family protein Bax has recently emerged as a promising new target in cancer therapy along with first BAX activators (BAM7, Compound 106, and SMBA1). "
2.	Friedreich Ataxia (Friedreich's Ataxia) 04/09/2008 - "We treated KIKI mice with a novel histone deacetylase inhibitor, compound 106, which substantially increases frataxin mRNA levels in cells from Friedreich ataxia individuals. "

1.	Histone Deacetylase Inhibitors
2.	Messenger RNA (mRNA)
3.	Proteins (Proteins, Gene)
4.	Frataxin

1.	Therapeutics