jaridonin

04/01/2016 - "Jaridonin can significantly induce G(2)/M arrest in gastric cancer MGC-803 cells. "
04/01/2016 - "To study the effects of Jaridonin, a novel diterpenoid from isodon rubescens, on the cell cycle of human gastric cancer cells and its molecular mechanism of action. "
04/01/2016 - "[Jaridonin, a new diterpenoid from Isodon rubescens, induces cell cycle arrest in gastric cancer cells through activating ataxia telangiectasia mutated kinase]."

01/15/2015 - "In conclusion, these findings identified that Jaridonin-induced cell cycle arrest in human esophageal cancer cells is associated with ROS-mediated activation of ATM-Chk1/2-Cdc25C pathway. "
01/01/2015 - "Jaridonin selectively induces apoptosis in esophageal cancer EC-1 cells through H2O2-mediated DNA damage by depleting GSH."
01/01/2015 - "[Jaridonin induces apoptosis in human esophageal cancer cells by depleting GSH and inducing DNA damage]."
07/01/2013 - "Jaridonin potently reduced viabilities of several esophageal cancer cell lines, including EC109, EC9706 and EC1. "
01/15/2015 - "Jaridonin-induced G2/M phase arrest in human esophageal cancer cells is caused by reactive oxygen species-dependent Cdc2-tyr15 phosphorylation via ATM-Chk1/2-Cdc25C pathway."

01/15/2015 - "Jaridonin, a novel diterpenoid from Isodon rubescens, has been shown previously to inhibit proliferation of esophageal squamous cancer cells (ESCC) through G2/M phase cell cycle arrest. "

04/01/2016 - "Flow cytometry was used to analyze the cell cycle distribution and expression of ataxia telangiectasia mutated kinase (ATM) after Jaridonin treatment. "
04/01/2016 - "[Jaridonin, a new diterpenoid from Isodon rubescens, induces cell cycle arrest in gastric cancer cells through activating ataxia telangiectasia mutated kinase]."