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methylated actinomycin D

methylated at position 7 of the phenoxazone ring; structure in first source

Also Known As:

mActD compound

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Dactinomycin: 2073
      - methylated actinomycin D: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Dactinomycin: 2073
      - methylated actinomycin D: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Dactinomycin: 2073
      - methylated actinomycin D: 1

Experts

1.	Bian, Guangkai: 1 article (12/2013)
2.	Cao, Chengliang: 1 article (12/2013)
3.	Cao, Xiaoying: 1 article (12/2013)
4.	Chen, Yongqiang: 1 article (12/2013)
5.	Jiang, Jihong: 1 article (12/2013)
6.	Liu, Jinjuan: 1 article (12/2013)
7.	Qin, Sheng: 1 article (12/2013)
8.	Wang, Zhe: 1 article (12/2013)
9.	Yuan, Bo: 1 article (12/2013)

Related Diseases

1.

Neoplasms (Cancer)

12/01/2013 - "In the present study, we reported that methylated actinomycin D (mAct D), a novel actinomycin D analog isolated from Streptomyces sp. KLBMP 2541 in our previous study, could not only exert stronger inhibitory effects on several human cancer cells than Act D in dose- and time-dependent manner at ng concentrations, especially on HepG2 cells, but also lower cytotoxicity in normal cells (HL-7702). "

Related Drugs and Biologics

1.	Dactinomycin (Actinomycin)