naphthalene-1-carboxylic acid (3'- chloro- 4'- fluoro- 4- piperazin- 1- yl- biphenyl- 3- yl)amide

a BACE1 inhibitor; structure in first source

Also Known As:

NCFB compound

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Alzheimer Disease (Alzheimer's Disease) 07/01/2013 - "As a first trial for in vivo imaging of β-secretase (BACE1) in Alzheimer's disease brain, we applied a novel non-peptidergic small molecule which has high affinity to the enzyme, naphthalene-1-carboxylic acid (3'-chloro-4'-fluoro-4-piperazin-1-yl-biphenyl-3-yl)amide (NCFB) into positron emission tomography (PET) probe. "

1.	Amyloid Precursor Protein Secretases (beta-Secretase)
2.	Enzymes