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amphidinolide B2
originally from Amphidinium sp.; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Lactones: 1549
Macrolides: 4391
Amphidinolides: 2
amphidinolide B2: 1
Polyketides: 231
Macrolides: 4391
Amphidinolides: 2
amphidinolide B2: 1
Polycyclic Compounds: 6
Macrocyclic Compounds: 15
Polyketides: 231
Macrolides: 4391
Amphidinolides: 2
amphidinolide B2: 1
Experts
1.
Carter, Rich G
: 1 article (03/2013)
2.
Horne, David A
: 1 article (03/2013)
3.
Jove, Richard
: 1 article (03/2013)
4.
Lu, Liang
: 1 article (03/2013)
5.
Nam, Sangkil
: 1 article (03/2013)
6.
Zhang, Wei
: 1 article (03/2013)
Related Diseases
1.
Prostatic Neoplasms (Prostate Cancer)
03/15/2013 - "
Of the different stereoisomers, the proposed structure of amphidinolide B2 is over 12-fold more potent than the C8,9-epimer and C18-epimer in human DU145 prostate cancer cells.
"
2.
Neoplasms (Cancer)
03/15/2013 - "
The originally proposed structure for amphidinolide B2 and diastereomers thereof display potent antitumor activities with IC50 values ranging from 3.3 to 94.5 nM against human solid and blood tumor cells.
"