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5- N,6- O- (N''- octyliminomethylidene)nojirimycin

structure in first source

Also Known As:

NOI-NJ

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Aguilar-Moncayo, Matilde: 1 article (06/2011)
2.	Aviezer, David: 1 article (06/2011)
3.	Benito, Juan M: 1 article (06/2011)
4.	Brumshtein, Boris: 1 article (06/2011)
5.	Futerman, Anthony H: 1 article (06/2011)
6.	García Fernandez, José M: 1 article (06/2011)
7.	Ortiz Mellet, Carmen: 1 article (06/2011)
8.	Shaaltiel, Yoseph: 1 article (06/2011)
9.	Silman, Israel: 1 article (06/2011)
10.	Sussman, Joel L: 1 article (06/2011)

Related Diseases

1.

Gaucher Disease (Gaucher's Disease)

06/07/2011 - "Attempts to co-crystallize GlcCerase with 5-N,6-O-[N'-(n-octyl)iminomethylidene]nojirimycin (NOI-NJ) or with 5-N,6-S-[N'-(n-octyl)iminomethylidene]-6-thionojirimycin (6S-NOI-NJ), two potent inhibitors of the enzyme with promising pharmacological chaperone activity for several Gaucher disease-associated mutations, were unsuccessful probably due to the formation of aggregates that increase the heterogeneity of the sample and affect nucleation and growth of crystals. "

Related Drugs and Biologics

1.	Enzymes
2.	nojirimycin