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ON 013105

inhibits benzylstyryl sulfone kinase; structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Styrenes: 6
        ON 013105: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - ON 013105: 1

Experts

1.	Gillum, Amanda M: 1 article (01/2013)
2.	Groopman, Jerome E: 1 article (01/2013)
3.	Kumar, Ramesh: 1 article (01/2013)
4.	Kuzontkoski, Paula M: 1 article (01/2013)
5.	Papadopoulos, Evangelos: 1 article (01/2013)
6.	Prasad, Anil: 1 article (01/2013)
7.	Reddy, E Premkumar: 1 article (01/2013)
8.	Reddy, M V Ramana: 1 article (01/2013)
9.	Shrivastava, Ashutosh: 1 article (01/2013)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2013 - "Efficacy studies in a mouse xenograft model showed that ON 013105 inhibited MCL tumor growth and that combining ON 013105 with rituximab reduced tumor burden further with negligible unwanted effects. " 01/01/2013 - "Combined administration of rituximab and on 013105 induces apoptosis in mantle cell lymphoma cells and reduces tumor burden in a mouse model of mantle cell lymphoma."
2.	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/01/2013 - "Combined administration of rituximab and on 013105 induces apoptosis in mantle cell lymphoma cells and reduces tumor burden in a mouse model of mantle cell lymphoma."

Related Drugs and Biologics

1.	Rituximab (Mabthera)