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9- methyl- 2- (oxiran- 2- ylmethoxy)- 9H- carbazole

structure in first source

Also Known As:

MHY407

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Carbazoles: 32
        9-methyl-2-(oxiran-2-ylmethoxy)-9H-carbazole: 1
  - 3-Ring Heterocyclic Compounds
    - Carbazoles: 32
      - 9-methyl-2-(oxiran-2-ylmethoxy)-9H-carbazole: 1
Organic Chemicals: 133
- Ethers: 242
  - Cyclic Ethers: 12
    - Epoxy Compounds: 689
      - 9-methyl-2-(oxiran-2-ylmethoxy)-9H-carbazole: 1

Experts

1.	Ahn, Mee Young: 1 article (12/2012)
2.	Choi, Gayoung: 1 article (12/2012)
3.	Kim, Hyung Sik: 1 article (12/2012)
4.	Kim, Ju-Hwa: 1 article (12/2012)
5.	Kim, Won Ki: 1 article (12/2012)
6.	Lee, Hye Jin: 1 article (12/2012)
7.	Lee, Young Ju: 1 article (12/2012)
8.	Moon, Hyung Ryong: 1 article (12/2012)
9.	Yang, Zunhua: 1 article (12/2012)
10.	Yoon, Sungpil: 1 article (12/2012)

Related Diseases

1.	Neoplasms (Cancer) 12/15/2012 - "In this study, we synthesized a novel carbazole derivative, MHY407, as a sensitizer of cancer cells to increase DNA damage. " 12/15/2012 - "In addition, MHY407 also sensitized the cancer cells to DNA damaging radiation treatment. " 12/15/2012 - "A novel carbazole derivative, MHY407, sensitizes cancer cells to doxorubicin-, etoposide-, and radiation treatment via DNA damage."
2.	Breast Neoplasms (Breast Cancer) 12/15/2012 - "We then evaluated the anticancer effects of MHY407 and identified the molecular mechanism for the sensitization of breast cancer cell lines. " 12/15/2012 - "Furthermore, in doxorubicin and etoposide-treated breast cancer cells, co-treatment with MHY407 reduced cell viability and increased apoptosis. "

Related Drugs and Biologics

1.	carbazole
2.	Etoposide (VP 16)
3.	Doxorubicin (Adriamycin)
4.	DNA (Deoxyribonucleic Acid)

Related Therapies and Procedures

1.	Radiotherapy