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jacaric acid

has antineoplastic activity; a conjugated fatty acid isolated from jacaranda seed oil; 18:3(8c,10t,12c)

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Essential Fatty Acids: 734
      - Linolenic Acids: 96
        jacaric acid: 5

Experts

1.	Leung, Kwok Nam: 2 articles (01/2015 - 01/2015)
2.	Liu, Wai Nam: 2 articles (01/2015 - 01/2015)
3.	Leung, Kwok-Nam: 1 article (11/2014)
4.	Liu, Wai-Nam: 1 article (11/2014)
5.	Gasmi, Jihane: 1 article (06/2013)
6.	Thomas Sanderson, J: 1 article (06/2013)
7.	Honma, Taro: 1 article (01/2013)
8.	Ikezaki, Aya: 1 article (01/2013)
9.	Ito, Junya: 1 article (01/2013)
10.	Kijima, Ryo: 1 article (01/2013)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2013 - "We have shown previously that jacaric acid (JA; 8c,10t,12c-18:3), which has a conjugated triene system, has a strong anti-tumor effect. " 01/01/2015 - "This study aims at demonstrating the in vitro anti-tumor effect and action mechanisms of jacaric acid, a CLN isomer which is present in jacaranda seed oil, on the murine macrophage-like leukemia PU5-1.8 cells. "
2.	Leukemia 01/01/2015 - "Jacaric acid inhibits the growth of murine macrophage-like leukemia PU5-1.8 cells by inducing cell cycle arrest and apoptosis." 11/01/2014 - "Collectively, our results demonstrated the capability of jacaric acid to inhibit the growth of EoL-1 cells in vitro through triggering cell cycle arrest and by inducing apoptosis and differentiation of the leukemia cells. " 01/01/2015 - "This study aims at demonstrating the in vitro anti-tumor effect and action mechanisms of jacaric acid, a CLN isomer which is present in jacaranda seed oil, on the murine macrophage-like leukemia PU5-1.8 cells. "
3.	Myeloid Leukemia (Leukemia, Myelocytic) 01/01/2015 - "Therefore, jacaric acid is a potential candidate for the treatment of some forms of myeloid leukemia with minimal toxicity and fewer side effects." 11/01/2014 - "Therefore, jacaric acid might be developed as a potential candidate for the treatment of certain forms of myeloid leukemia with minimal toxicity and few side effects. "
4.	Hypereosinophilic Syndrome (Loeffler Endocarditis) 11/01/2014 - "Apoptosis- and differentiation-inducing activities of jacaric acid, a conjugated linolenic acid isomer, on human eosinophilic leukemia EoL-1 cells."
5.	T-Cell Lymphoma (Lymphoma, T Cell) 01/01/2015 - "Our results showed that jacaric acid exhibited no significant cytotoxicity on the thioglycollate-elicited murine peritoneal macrophages as revealed by the neutral red uptake assay, but markedly increased their cytostatic activity on the T-cell lymphoma MBL-2 cells as measured by the fluorometric CyQuant® NF Cell Proliferation Assay Kit. "

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