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24,25,26,27- tetranor- apotirucalla- (apoeupha)- 1- senecioyloxy- 3,7- dihydroxy- 14,20,22- trien- 21,23- epoxy

an antidiabetic agent isolated from Azadirachta indica; structure in first source

Also Known As:

meliacinolin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Sterols: 2245
        Phytosterols: 1069
        24,25,26,27-tetranor-apotirucalla-(apoeupha)-1-senecioyloxy-3,7-dihydroxy-14,20,22-trien-21,23-epoxy: 1
Lipids: 114793
- Membrane Lipids: 1591
  - Sterols: 2245
    - Phytosterols: 1069
      - 24,25,26,27-tetranor-apotirucalla-(apoeupha)-1-senecioyloxy-3,7-dihydroxy-14,20,22-trien-21,23-epoxy: 1
Biological Factors: 2472
- Phytochemicals: 5771
  - Phytosterols: 1069
    - 24,25,26,27-tetranor-apotirucalla-(apoeupha)-1-senecioyloxy-3,7-dihydroxy-14,20,22-trien-21,23-epoxy: 1

Experts

1.	Damian-Guzman, Monica: 1 article (01/2012)
2.	Perez-Gutierrez, Rosa Martha: 1 article (01/2012)

Related Diseases

1.	Insulin Resistance 01/01/2012 - "We conclude that meliacinolin can efficiently inhibit insulin resistance, improvement of renal function, lipid abnormalities, and oxidative stress, indicating that its therapeutic properties may be due to the interaction of meliacinolin with multiple targets involved in diabetes pathogenesis. "
2.	Type 2 Diabetes Mellitus (MODY) 01/01/2012 - "Meliacinolin: a potent α-glucosidase and α-amylase inhibitor isolated from Azadirachta indica leaves and in vivo antidiabetic property in streptozotocin-nicotinamide-induced type 2 diabetes in mice."

Related Drugs and Biologics

1.	Streptozocin (Streptozotocin)
2.	Niacinamide (Nicotinamide)
3.	Lipids
4.	Hypoglycemic Agents (Hypoglycemics)
5.	Glucosidases
6.	Amylases