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4- amino- 1- (3,4- dihydroxy- 5- (hydroxymethyl)- 3- methyltetrahydrofuran- 2- yl)pyrimidin- 2(1H)- one

has antiviral activity

Also Known As:

2'-C-MeC; NM-107

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Cytidine: 535
        Deoxycytidine: 307
        4-amino-1-(3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Cytidine: 535
      - Deoxycytidine: 307
        4-amino-1-(3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one: 1
  - Deoxyribonucleosides: 34
    - Deoxycytidine: 307
      - 4-amino-1-(3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one: 1

Experts

1.	Bassit, Leda: 1 article (01/2008)
2.	Bennett, Matthew: 1 article (01/2008)
3.	Grier, Jason: 1 article (01/2008)
4.	Schinazi, Raymond F: 1 article (01/2008)

Related Diseases

1.	Infections 01/01/2008 - "These promising in vitro data warrant clinical investigation of the nucleosides analogues such as 2'-C-MeC or 2'-F-C-MeC in their prodrug forms, together with IFN-alphac2b and RBV, for successful treatment of HCV infections."

Related Drugs and Biologics

1.	Prodrugs
2.	Nucleosides