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4- (2,6- dimethyl- 4- (4- trifluoromethoxyphenyl)piperazine- 1- sulfonyl)indan- 2- carboxylic acid

structure in first source

Also Known As:

KD3010

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - 4-(2,6-dimethyl-4-(4-trifluoromethoxyphenyl)piperazine-1-sulfonyl)indan-2-carboxylic acid: 1
Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - 4-(2,6-dimethyl-4-(4-trifluoromethoxyphenyl)piperazine-1-sulfonyl)indan-2-carboxylic acid: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - 4-(2,6-dimethyl-4-(4-trifluoromethoxyphenyl)piperazine-1-sulfonyl)indan-2-carboxylic acid: 1

Experts

1.	Brenner, David A: 1 article (05/2012)
2.	Downes, Michael: 1 article (05/2012)
3.	Evans, Ronald M: 1 article (05/2012)
4.	Haimerl, Michael: 1 article (05/2012)
5.	Iwaisako, Keiko: 1 article (05/2012)
6.	Kodama, Yuzo: 1 article (05/2012)
7.	Paik, Yong-Han: 1 article (05/2012)
8.	Schnabl, Bernd: 1 article (05/2012)
9.	Sirlin, Claude: 1 article (05/2012)
10.	Taura, Kojiro: 1 article (05/2012)

Related Diseases

1.	Starvation 05/22/2012 - "The hepatoprotective and antifibrotic effect of KD3010 was confirmed in a model of cholestasis-induced liver injury and fibrosis using bile duct ligation for 3 wk. Primary hepatocytes treated with KD3010 but not GW501516 were protected from starvation or CCl(4)-induced cell death, in part because of reduced reactive oxygen species production. "
2.	Fibrosis (Cirrhosis) 05/22/2012 - "The hepatoprotective and antifibrotic effect of KD3010 was confirmed in a model of cholestasis-induced liver injury and fibrosis using bile duct ligation for 3 wk. Primary hepatocytes treated with KD3010 but not GW501516 were protected from starvation or CCl(4)-induced cell death, in part because of reduced reactive oxygen species production. "
3.	Cholestasis 05/22/2012 - "The hepatoprotective and antifibrotic effect of KD3010 was confirmed in a model of cholestasis-induced liver injury and fibrosis using bile duct ligation for 3 wk. Primary hepatocytes treated with KD3010 but not GW501516 were protected from starvation or CCl(4)-induced cell death, in part because of reduced reactive oxygen species production. "

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	GW 501516

Related Therapies and Procedures

1.	Ligation