inauzhin

01/01/2015 - "Previously, we showed that inauhzin (INZ) activates p53 and inhibits tumor growth. "
05/01/2013 - "Inauhzin sensitizes p53-dependent cytotoxicity and tumor suppression of chemotherapeutic agents."
08/01/2012 - "Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth."
01/01/2012 - "We recently identified Inauhzin (INZ) as a novel p53 activator, selectively and efficiently suppressing tumor growth without displaying genotoxicity and with little toxicity to normal cells. "
08/01/2012 - "In this study, we tested if combining Inauhzin with Nutlin-3, an inhibitor of MDM2-p53 binding, might synergistically activate p53 to suppress tumor growth. "

01/01/2022 - "We hereby employed quantitative acetyl-proteomics to globally reveal the landscape of SIRT1-dependent acetylation in colorectal cancer (CRC) cells stimulated by specific SIRT1 inhibitor Inauhzin (INZ). "

08/01/2012 - "Indeed, at lower doses, combination of Inauhzin and Nutlin-3 exhibited a synergistic effect on inhibiting cell growth and promoting apoptosis in human colon and lung cancer cell lines in a p53-dependent fashion. "

07/01/2022 - "Calcium-oxidative stress signaling axis and casein kinase 1α mediate eryptosis and hemolysis elicited by novel p53 agonist inauhzin."