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GNX-686

structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Maleates: 3
        Maleimides: 16
        GNX-686: 1
- Imides: 79
  - Maleimides: 16
    - GNX-686: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - Maleimides: 16
        GNX-686: 1

Experts

1.	Ballini, Jean-Pierre: 1 article (03/2012)
2.	Cataudella, Tiziana: 1 article (03/2012)
3.	Gatz, Randall: 1 article (03/2012)
4.	Giorgio, Marco: 1 article (03/2012)
5.	Nowak-Sliwinska, Patrycja: 1 article (03/2012)
6.	Plyte, Simon: 1 article (03/2012)
7.	Storto, Mariangela: 1 article (03/2012)
8.	Wagnières, Georges: 1 article (03/2012)
9.	van den Bergh, Hubert: 1 article (03/2012)

Related Diseases

1.

Neoplasms (Cancer)

03/01/2012 - "In vitro studies on HUVEC showed that GNX-686 inhibited cell growth with an ED(50) of 20-25 μM, while human HeLa tumor cells and non-transformed embryonic mouse fibroblasts were less sensitive for the drug. "
03/01/2012 - "Taken together these results demonstrate that GNX-686 is a promising anti-angiogenic compound that could be developed for the treatment of diseases characterized by aberrant angiogenesis such as ocular pathologies and cancer."