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LDE223

inhibitor of smoothened (Smo)

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        LDE223: 1

Experts

1.	Akhmetshina, Alfiya: 1 article (05/2012)
2.	Beyer, Christian: 1 article (05/2012)
3.	Cordazzo, Cinzia: 1 article (05/2012)
4.	Dees, Clara: 1 article (05/2012)
5.	Distler, Jörg H W: 1 article (05/2012)
6.	Distler, Oliver: 1 article (05/2012)
7.	Horn, Angelika: 1 article (05/2012)
8.	Kireva, Trayana: 1 article (05/2012)
9.	Palumbo-Zerr, Katrin: 1 article (05/2012)
10.	Ruat, Martial: 1 article (05/2012)

Related Diseases

1.	Fibrosis (Cirrhosis) 05/01/2012 - "Hedgehog signalling was inhibited by the selective inhibitor LDE223 and by small interfering RNA against Smo in the models of bleomycin-induced dermal fibrosis and in tight-skin-1 mice. "

Related Drugs and Biologics

1.	Small Interfering RNA (siRNA)
2.	Bleomycin (Blenoxane)