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2- (3- chlorophenyloamino)- 5- (2,4- dihydroxyphenyl)- 1,3,4- thiadiazole

structure in first source

Also Known As:

4ClABT

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - Thiadiazoles: 99
      - 2-(3-chlorophenyloamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Thiadiazoles: 99
        2-(3-chlorophenyloamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole: 2

Experts

1.	Niewiadomy, Andrzej: 2 articles (12/2020 - 01/2011)
2.	Karpińska, Monika: 1 article (12/2020)
3.	Rola, Radosław: 1 article (12/2020)
4.	Szeliga, Monika: 1 article (12/2020)
5.	Juszczak, Małgorzata: 1 article (01/2011)
6.	Matysiak, Joanna: 1 article (01/2011)
7.	Rzeski, Wojciech: 1 article (01/2011)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2011 - "Morphological changes induced by 4ClABT in cancer and normal cells were analyzed in HE staining specimens. " 12/01/2020 - "Previous studies have shown that 2-(4-fluorophenyloamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole (FPDT) and 2-(3-chlorophenyloamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole (CPDT) diminished viability of cancer cell lines of different origin. " 01/01/2011 - "The aim of this study was an in vitro evaluation of the anti-cancer activity of a new synthesized aminothiadiazole derivative 2-(3-chlorophenyloamino)-5-(2,4-dihydroxyphenyl)- -1,3,4-thiadiazole 4ClABT. " 01/01/2011 - "The activity of a new 2-amino-1,3,4-thiadiazole derivative 4ClABT in cancer and normal cells." 01/01/2011 - "The antiproliferative activity of 4ClABT in tumor cells derived from peripheral cancers including breast carcinoma (T47D), colon carcinoma (HT-29), thyroid carcinoma (FTC-238), teratoma (P19), and T-cell leukemia (Jurkat E6.1), as well as cancers of the nervous system including rhabdomyosarcoma/medulloblastoma (TE671), brain astrocytoma (MOGGCCM) and glioma (C6) was studied by means of MTT assay. "
2.	T-Cell Leukemia (Leukemia, T Cell) 01/01/2011 - "The antiproliferative activity of 4ClABT in tumor cells derived from peripheral cancers including breast carcinoma (T47D), colon carcinoma (HT-29), thyroid carcinoma (FTC-238), teratoma (P19), and T-cell leukemia (Jurkat E6.1), as well as cancers of the nervous system including rhabdomyosarcoma/medulloblastoma (TE671), brain astrocytoma (MOGGCCM) and glioma (C6) was studied by means of MTT assay. "
3.	Thyroid Neoplasms (Thyroid Cancer) 01/01/2011 - "The antiproliferative activity of 4ClABT in tumor cells derived from peripheral cancers including breast carcinoma (T47D), colon carcinoma (HT-29), thyroid carcinoma (FTC-238), teratoma (P19), and T-cell leukemia (Jurkat E6.1), as well as cancers of the nervous system including rhabdomyosarcoma/medulloblastoma (TE671), brain astrocytoma (MOGGCCM) and glioma (C6) was studied by means of MTT assay. "
4.	Teratoma (Teratoid Tumor) 01/01/2011 - "The antiproliferative activity of 4ClABT in tumor cells derived from peripheral cancers including breast carcinoma (T47D), colon carcinoma (HT-29), thyroid carcinoma (FTC-238), teratoma (P19), and T-cell leukemia (Jurkat E6.1), as well as cancers of the nervous system including rhabdomyosarcoma/medulloblastoma (TE671), brain astrocytoma (MOGGCCM) and glioma (C6) was studied by means of MTT assay. "
5.	Rhabdomyosarcoma 01/01/2011 - "The antiproliferative activity of 4ClABT in tumor cells derived from peripheral cancers including breast carcinoma (T47D), colon carcinoma (HT-29), thyroid carcinoma (FTC-238), teratoma (P19), and T-cell leukemia (Jurkat E6.1), as well as cancers of the nervous system including rhabdomyosarcoma/medulloblastoma (TE671), brain astrocytoma (MOGGCCM) and glioma (C6) was studied by means of MTT assay. "

Related Drugs and Biologics

1.	Clostridium perfringens delta-toxin (CPDT)
2.	2-amino-1,3,4-thiadiazole