alpha-Macroglobulins

Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters.

Also Known As:

45S RNP; Acute-Phase alpha 1-Protein; Slow alpha 2-Globulin; alpha 1-Acute Phase Globulin; alpha 1-Acute Phase Protein; alpha 1-Macroglobulin; alpha 2-Acute Phase Globulin; alpha-Macrofetoprotein; Acute Phase alpha 1 Protein; RNP, 45S; Slow alpha 2 Globulin; Slow alpha 2 Macroglobulins; alpha 1 Acute Phase Globulin; alpha 1 Acute Phase Protein; alpha 1 Macroglobulin; alpha 1-Protein, Acute-Phase; alpha 2 Acute Phase Globulin; alpha 2 Acute Phase Globulins; alpha 2-Globulin, Slow; alpha 2-Macroglobulins, Slow; alpha Macrofetoprotein; alpha Macrofetoproteins; alpha Macroglobulins; Slow alpha 2-Macroglobulins; alpha 2-Acute Phase Globulins; alpha-Macrofetoproteins

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Acute-Phase Proteins: 5159
      - alpha-Macroglobulins: 31
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        alpha-Macroglobulins: 31
      - Macroglobulins: 53
        alpha-Macroglobulins: 31
  - Globulins: 3062
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        alpha-Macroglobulins: 31
      - Macroglobulins: 53
        alpha-Macroglobulins: 31

1.	Chronic Obstructive Pulmonary Disease (COPD) 09/01/1993 - "[Chronic obstructive lung disease and alpha-2-macroglobulin deficiency in serum--case report]."
2.	Prostatic Neoplasms (Prostate Cancer) 01/01/1985 - "Alpha-2-macroglobulin deficiency in patients with advanced prostate cancer."

alpha-2-Macroglobulin Deficiency

Bio-Agent Context: Research Results

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