Type 1 Generalized Epilepsy With Febrile Seizures Plus

mutation in SCN1B

Also Known As:

Generalized Epilepsy With Febrile Seizures Plus, Type 1; GEFS, Type 1; GEFSP1

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Epileptic Syndromes

1.	Isom, Lori L: 1 article (12/2002)
2.	Kazen-Gillespie, Kristin A: 1 article (12/2002)
3.	Koopman, Matthew C: 1 article (12/2002)
4.	Kriegler, Steven: 1 article (12/2002)
5.	Loukas, Andrew: 1 article (12/2002)
6.	Malhotra, Jyoti: 1 article (12/2002)
7.	Meadows, Laurence S: 1 article (12/2002)
8.	Ragsdale, David S: 1 article (12/2002)
9.	Thyagarajan, Veena: 1 article (12/2002)
10.	Conti, F: 1 article (03/2001)

Drugs and Important Biological Agents (IBA) related to Type 1 Generalized Epilepsy With Febrile Seizures Plus:

1.	Sodium Channels (Sodium Channel)IBA 12/15/2002 - "Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1." 03/23/2001 - "The syndrome of generalized epilepsy with febrile seizures plus type 1 (GEFS+) has been associated to the gene SCN1B coding for the sodium channel beta1 subunit (Wallace, R. "
2.	Voltage-Gated Sodium ChannelsIBA 12/15/2002 - "Generalized epilepsy with febrile seizures plus type 1 is an inherited human epileptic syndrome, associated with a cysteine-to-tryptophan (C121W) mutation in the extracellular immunoglobin domain of the auxiliary beta1 subunit of the voltage-gated sodium channel. "
3.	Tryptophan (L-Tryptophan)FDA Link 12/15/2002 - "Generalized epilepsy with febrile seizures plus type 1 is an inherited human epileptic syndrome, associated with a cysteine-to-tryptophan (C121W) mutation in the extracellular immunoglobin domain of the auxiliary beta1 subunit of the voltage-gated sodium channel. "
4.	Cysteine (L-Cysteine)FDA Link 12/15/2002 - "Generalized epilepsy with febrile seizures plus type 1 is an inherited human epileptic syndrome, associated with a cysteine-to-tryptophan (C121W) mutation in the extracellular immunoglobin domain of the auxiliary beta1 subunit of the voltage-gated sodium channel. "